The analysis of specific differences in the molecular responses to axotomy of supporting cells in the vicinity of PNS and CNS axons may help to elucidate the mechanisms that limit the ability of central axons to regenerate.doi:10.1007/978-3-642-71381-1_38H. W. Müller...
Given the location of SGCs in the PNS, these cells can be readily targeted with CNS-impermeable drugs, including biologics (e.g., monoclonal antibodies), thereby providing more options and avoiding the side effects of many CNS drugs (e.g., mood changes, anxiety, dizziness, sleep disturbance...
Given the location of SGCs in the PNS, these cells can be readily targeted with CNS-impermeable drugs, including biologics (e.g., monoclonal antibodies), thereby providing more options and avoiding the side effects of many CNS drugs (e.g., mood changes, anxiety, dizziness, sleep disturbance...