W. Role of glia-derived cholesterol in synaptogenesis: new revelations in the synapse-glia affair. J. Physiol. Paris. 96, 257–263 (2002). 34. Pfrieger, F. W. Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays. 25, 72–78 (2003). 35. Chung...
Astrocytes play crucial roles in brain homeostasis and are regulatory elements of neuronal and synaptic physiology. Astrocytic alterations have been found in Major Depressive Disorder (MDD) patients; however, the consequences of astrocyte Ca2+signaling in MDD are poorly understood. Here, we found that ...
The hypothesis that astrocytes could affect synaptogenesis by regulating voltage-gate...Glutamate-mediated astrocyte-neuron signaling. Nature 369: 744–747 - Parpura, TA, et al. - 1994 () Citation Context ...re credited. release of gliotransmitters, in particular ATP, that can signal other ...
20, 2835–2844 (2000) Astrocyte–neuron interactions in neurological disorders 333 54. Fam, S.R., Gallagher, C.J., Salter, M.W.: P2Y(1) purinoceptor mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes. J. Neurosci. 20, 2800–2808 (2000) 55. ...
Our findings have uncovered new functions for astrocytic S1PR1 signaling in regulation of bi‐directional astrocyte–neuron crosstalk at the nexus of astrocyte morphogenesis and synaptogenesis.doi:10.1002/glia.24135Sandeep K. SinghVirginia Commonwealth University School of Medicine,Richmond,Virginia,USATomasz...
Astrocytes play crucial roles in brain homeostasis and are regulatory elements of neuronal and synaptic physiology. Astrocytic alterations have been found in Major Depressive Disorder (MDD) patients; however, the consequences of astrocyte Ca2+ signaling
Astrocytes have long been considered as just providing trophic support for neurons in the central nervous system, but recently several studies have highlighted their importance in many functions such as neurotransmission, metabolite and electrolyte homeostasis, cell signaling, inflammation, and synapse modula...
in order to maintain their physiological functions, such as synaptogenesis, neurite outgrowth, and repair of damaged membranes [20]. Since adult neurons progressively lose their endogenous cholesterol synthesis capacity and do not contribute anymore to the overall cholesterol synthesis in the brain [21]...