Volterra A, Liaudet N, Savtchouk I. 2014. Astrocyte Ca2+ signalling: an unexpected complexity. Nature Reviews Neuroscience 15:327-335. DOI: https://doi.org/10.1038/nrn3725, PMID: 24739787Volterra A , Liaudet N , Savtchouk I. 2014 . Astrocyte Ca(2)(+) signaling: An unexpected ...
Astrocytes play crucial roles in brain homeostasis and are regulatory elements of neuronal and synaptic physiology. Astrocytic alterations have been found in Major Depressive Disorder (MDD) patients; however, the consequences of astrocyte Ca2+signaling in MDD are poorly understood. Here, we found that ...
人类的星形胶质细胞比啮齿类动物的大20多倍,形成的突触数量是啮齿类动物的10多倍。 自1990年代中期的研究表明,星形胶质细胞受到刺激时可在细胞间远距离传播Ca2+波,并且,类似于神经元,以Ca2+依赖的方式释放神经递质(称为胶质递质 (Gliotransmitter))。数据表明,星形胶质细胞还会通过钙离子依赖的路径释放谷氨酸,向神经元...
c), which was absent in a control condition in which the GCaMP was illuminated with isosbestic excitation light (405 nm) (Fig.2b, d)45,46. The astrocyte Ca2+activity was high during both wakefulness and rapid-eye-movement (REM) sleep and low during non-REM (NREM...
Many of these receptors are of metabotropic type, being associated with G proteins that, upon activation, stimulate phospholipase C and formation of inositol (1,4,5)-tr 星形细胞Ca2+信号的突触神经的控制根据事实星形细胞表达各种各样的功能神经传送体感受器官。 许多这些感受器官是metabotropic类型,同,在...
Reproducibility and comparability of models for astrocyte Ca2+ excitability (Manninen et al 2017) astrocyte oscillations-signaling-pathways-calcium-dynamics python-web-link-to-model Updated Dec 23, 2023 ModelDBRepository / 267696 Star 0 Code Issues Pull requests Glial voltage dynamics driven by ...
Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling. Agulhon C, Fiacco TA and McCarthy KD (2010) Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling. Science 327:... Cendra,Agulhon,Todd,... - 《Science》 被引量:...
Astrocyte Intracellular Ca2+and TrkB Signaling in the Hippocampus Could Be Involved in the Beneficial Behavioral Effects of Antidepressant Treatment Astrocyte Intracellular Ca2+and TrkB Signaling in the Hippocampus Could Be Involved in the Beneficial Behavioral Effects of Antidepressant Treatment... FR ...
Ca2+ oscillations in astrocytic endfeet can control cerebral microcirculation through the arachidonic acid metabolites prostaglandin E2 and epoxyeicosatrienoic acids that induce arteriole dilation, and 20-HETE that induces arteriole constriction. In addition to actions on the vasculature, the release of ...
We used two-photon laser scanning microscopy, electrophysiology, MINIscopes, RNA-seq, and a genetic approach to explore the effects of reduced striatal astrocyte Ca2+ signaling in vivo. In wild-type mice, reducing striatal astrocyte Ca2+-dependent signaling increased repetitive self-grooming behaviors...