Details of the development of conventional analytical methods for the determination of drugs in pediatric plasma/serum samples via microassays are presented. Examples of the development of small-volume sampling and the use of the newer detection systems such as LC/MS/MS for enhanced detection are ...
Additional drugs identified in breast milk but not quantified were secobarbital, ethosuxi- mide, codeine, methadone, tolbutamide and caffeine. No obvious e f f e c t s of the drugs were observed in these neonates, but breast milk may serve as a s i g n i f i c a n t route f ...
Using the assay, we undertook a drug repositioning screen to identify inhibitors of the IN–LEDGF/ p75 interaction from a library of US Food and Drug Administration (FDA)-approved drugs. We found that the assay developed was quite robust. It was also found that dexlansoprazole, which is ...
It's also been recommended to increase the use of the BMP biomarker in clinical trials of drugs that induce phospholipidosis (Willard and De Felice, 2016). In order to minimize the occurrence of drug-induced nephrotoxicity, it is necessary either to prevent new nephrotoxic drugs from entering ...
In addition, worldwide research on the comparability of biosimilar drugs is ushering in a new era of requirements. In the comparability study, it is very important to choose a method with high sensitivity, good reproducibility, and strong operability, especially with higher differential display. In...
5240862 Process and device for the separation of a body fluid from particulate materials August, 1993 Koenhen et al. 5238652 Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques August, 1993 Sun et al. 5236826 Immunoassay for the dete...
-GGAAACACATCCTCCATG-3albuminmatrixspraydryingTMSpectralanalysisvaryingdrugloadingformulationsbothdrugsmid-IRattenuatedtotalreflectance-Fouriertransforminfraredspectroscopy(ATR-FTIR).bendingvibration948cmmicroencapsulateddrugscalculatedpeakareascorrespondeddrugloadingsmicrosphereformulations.standardcurvecoulddrugcontentunknown...
In addition, Bingpian and synthetic Bingpian have attracted much attention because of its possible enhancement of the oral bioavailability of other drugs and medicinal herbal compounds[17, 18], and the passage across the blood brain bar- rier[19–21]. Borneol can be oxidized to camphor (1,7...
www.nature.com/scientificreports OPEN received: 21 September 2016 accepted: 14 February 2017 Published: 21 March 2017 A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels A. Menegon1,2, S. Pitassi3, N. ...
Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium. Stud. Mycol. 2004, 49, 201–241. Toxins 2016, 8, 235 11 of 12 9. Sanzani, S.M.; Montemurro, C.; di Rienzo, V.; Solfrizzo, M.; Ippolito, A. Genetic structure and natural variation ...