View and buy high purity CH 223191. Potent aryl hydrocarbon receptor (AhR) antagonist. Cited in 13 publications.
The present disclosure relates to an aryl hydrocarbon receptor antagonist such as substituted imidazopyridines and imidazopyrazines, and a method of amplifying hematopoietic stem cells by culturing hematopoietic stem cells or progenitor cells in the presence of such drugs.The present disclosure also ...
Aryl hydrocarbon receptor (AHR) antagonist that promotes the self-renewal of human hematopoietic stem cells (HSC) in culture. SR1 promotes the ex vivo expansion of CD34+ cells. Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that...
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR). 靶点活性 AhR:30 nM 体外活性 每天口服10 mg/kg CH-223191,能有效预防小鼠体内由四氯二苯并-p-二恶英引起的细胞色素P450诱导,消耗综合症和肝毒性. 体内活性 CH-223191下调人类胶质母细胞瘤细胞中TGF-β/ Smad通路,并降低...
H. Urolithin A Is a dietary microbiota-derived human aryl hydrocarbon receptor antagonist. Metabolites 8, 86 (2018). PubMed Central Google Scholar Poland, A. & Glover, E. Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles. Mol....
Citations (13) COA / SDS Potent aryl hydrocarbon receptor (AhR) antagonist Catalog # Availability Size / Price Qty Loading... Key Product Details Description:Potent aryl hydrocarbon receptor (AhR) antagonist Chemical Name:1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-...
StemRegenin 1 : Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment. ≥98% (HPLC).
(Fig.3d, upper panel). A synthetic flavone derivative AhR antagonist, alpha-naphthoflavone (ANF)34, inhibited BaP-induced PD-L1 at both mRNA (Fig.3e) and protein (Fig.3d, lower panel) levels. Since ANF also bears agonistic effect on AhR in that it can activate AhR targetCYP1A1promoter...
View and buy high purity CH 223191 from Tocris Bioscience. Potent aryl hydrocarbon receptor (AhR) antagonist. Cited in 13 publications.
View and buy high purity StemRegenin 1. Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment.