Aryl hydrocarbon receptor (AHR) research has shifted from exploring dioxin toxicity to elucidation of physiologic AHR functions. Control of AHR functions is challenged by the fact that AHR is often involved in balancing opposing processes. Two AHR functions are discussed. (i) Microbial defense: ...
Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function The aromatic hydrocarbon (Ah) receptor (AHR) is the only known cellular receptor of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and of many other...
Interestingly, beta tubulin has been shown to play a role in the AhR function in mammalian cells: it could reduce the binding of the AhR/Arnt (Ah receptor nuclear translocator) heterodimer to the DRE (dioxin response element) by interacting with Arnt but not the AhR (Zhang et al., 2010)...
Modulation of Th17 development and function by activation of the aryl hydrocarbon receptor—the role of endogenous ligands. Eur. J. Immunol. 39, 652–654 (2009). CAS PubMed Google Scholar Quintana, F. J. LeA(H)Rning self-control. Cell Res. 24, 1155–1156 (2014). CAS PubMed PubMed...
Zinc and plant-derived ligands of the aryl hydrocarbon receptor (AHR) are dietary components affecting intestinal epithelial barrier function. Here, we explore whether zinc and the AHR pathway are linked. We show that dietary supplementation with an AHR pre-ligand offers protection against inflammatory...
#exposome# aryl hydrocarbon receptor,简称AHR,多环芳烃受体在皮肤上的表达,解释了为什么皮肤会收到外界污染的干扰,导致最终皮肤屏障破损和炎症,以及色素产生增多的情况,更可怕的是这些污染物被紫外线活化之后,产生的损伤效应比单独两者要强无数倍,日间防护刻不容缓。 ...
Aryl hydrocarbon receptor Identifiers Symbol(s) AHR; External IDs OMIM: 600253 MGI: 105043 Homologene: 1224 Gene Ontology Molecular Function: • transcription factor activity • ligand-dependent nuclear receptor activity • protein binding Cellular Component: • nucleus • cytoplasm ...
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Exper... Purpose: Indole-3-aldehyde (IAld) has been shown to improve intestinal epithelial barrier (IEB) function through the aryl hydrocarbon receptor (...
上海玉博生物科技有限公司 主要致力于“Anti-Ah Receptor(Aryl Hydrocarbon Receptor) 芳香烃受体抗体 yb-1416R”的生产销售。多年的“Anti-Ah Receptor(Aryl Hydrocarbon Receptor) 芳香烃受体抗体 yb-1416R”生产与销售的经验,与各行业新老用户建立了稳定的合作关系
Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH) superfamily of transcription factors, which are associated with cellular responses to environmental stimuli, such as xenobiotics and oxygen levels. Unlike other members o