Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment? J Alzheimers Dis. 2012;30(2):S283-304.Frisardi V. Apolipoprotein E genotype: the innocent by- stander or active bridge between metabolic syndrome and cognitive impairment? J ...
Polymorphisms in the gene encoding apolipoprotein E (APOE) may partly explain this variability by altering transport of vitamin K to the liver. In a prospective cohort study of 232 individuals (52.2% Caucasian and 47.8% African American) initiating warfarin therapy, the weekly maintenance dose was ...
Apolipo- protein (apo) E genotype and apo E concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. J Lipid Res 1996;37:1316 - 24.Bohnet K, Pillot T, Visvikis S, Sabolovic N, Siest G. Apolipoprote in (apo) E genotype and apoE ...
apolipoprotein e epsilon 4 (apoe‐ε4) genotype is associated with decreased 6‐month verbal memory performance after mild traumatic brain injury(载脂蛋白eε4(apoeε4)基因型与轻度脑外伤后6个月记忆功能下降相关) 文档格式: .pdf 文档大小:
Apolipoprotein E (apoE) is implicated in both dementia and ischemic heart disease. • ApoE plays a pivotal role in lipoprotein metabolism in both brain and periphery. • ApoE plays both a qualitative and a quantitative role in these diseases. • The aim is to summarize the current evidence...
ArticlesAPOE genotype and HIE outcome functional outcome following cardiopulmonary resuscitation compared with adults with the less common minor alleles e4 and e2 (18,19). No study has reported whether neurological outcome, including CP, among infants with moderate to severe neonatal HIE who survive ...
Learning Outcome Participants will be able to understand the effect of Apo E genotype and supplemental dietary intervention in cardiovascular disease (CVD) related blood lipid levels in elderly Korean population. ApoE genotype influences blood lipid levels due to LDL receptor binding activity and lipoprot...
Mounting evidence suggests that the APOE4 protein isoform drives amyloid pathology and impairs multiple aspects of normal brain function, thereby increasing the risk of AD11 (Table 1). Studies have also shed light on the associations between APOE genotype and tau-mediated neurodegeneration12, the ...
E (apoE), in addition to being a central mediator of lipoprotein metabolism, has an ever increasing 'repertoire' of biological functions [1,2]. As will be reviewed here, accumulating evidence indicates that apoE genotype could be an important host genetic factor affecting infectious disease risk....
byAPOEgenotype. (B) Analysis of the presence of apoE4 in the validation cohort of 50 plasma samples by ELISA stratified byAPOEgenotype. (C) Analysis of the presence of apoE4 in the validation cohort of 50 samples by a turbidimetric assay stratified byAPOEgenotype. Error bars represent median...