Apolipoprotein E genotyping in Alzheimer's disease. By - G McKeith, C.M Morris, Simon Lovestone, Gordon Wilcock, Martin Rossor, Harry Cayton, Ian Ragan, S Humphries, D.J Betteridge, P.N Durrington,...doi:10.1016/S0197-4580(96)80240-5B. Engvall...
Multiplex T-ARMS PCR for APOE genotyping is a simple and accurate method that requires only a single PCR reaction, without any another treatments or expensive instrumentation, to simultaneously identify two sites of single nucleotide polymorphisms. 展开 ...
74 Biases may occur when recruitment and dropout occur continuously throughout studies,29 or when individuals do not consent to or are not available for genotyping. A notable example of ascertainment bias occurred in a study that compared participants sampled from a research clinic with participants ...
Apolipoprotein E genotyping in the diagnosis of Alzheimer's disease in autopsy confirmed series. Lancet 1996;348:483(Abstract)Kakulas BA, Wilton SD, Fabian VA, et al. Apolipoprotein-E genotyping in the diagnosis of Alzheimer's disease in autopsy confirmed series. Lancet 1996;348:483 (L...
Because not every family whose infant was enrolled in the Network's Hypothermia or aEEG studies was approached for con- sent for the APOE genotyping study from the time of initiation of the Hypothermia or aEEG study, we compared demographics and perinatal characteristics and events between those ...
Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to diseases. ApoE4 is an accepted risk factor for Alzheimer's disea...
Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to diseases. ApoE4 is an accepted risk factor for Alzheimer's disea...
Uric acid levels seem to discriminate subgroups at increased risk of systolic hypertension among the subjects with different genotypes containing the e2 allele and, together with apoE genotyping, determining its serum concen- tration could be helpful when preparing preventive action. CONFLICT OF INTEREST...
We investigated effects of apolipoprotein E (ApoE) ε4 genotype on Aβ and tau burden and their longitudinal changes in Alzheimer's disease spectrum. Among 272 individuals who underwent PET scans (18F‐florbetaben for Aβ and 18F‐flortaucipir for tau), and ApoE genotyping, 187 individuals ...
Apolipoprotein E and cognitive change in an elderly population. Ann Neurol. 1996;4055- 66Google ScholarCrossref 20. Roses AD Apolipoprotein E genotyping in the differential diagnosis, not prediction of Alzheimer's disease. Ann Neurol. 1995;386- 14Google ScholarCrossref 21. McKahnn GDrachman ...