A labeled opposite gene-specific oligonucleotide probe is then used for the resultant amplified DNA fragments to test the epsilon2, epsilon4, epsilon5 and epsilon7 types. Thereby, the apolipoprotein E genotype is tested.TOYOSATO MITSUYOSHIKOSAKA TETSUYA...
The e4 allele has been associated with cerebral palsy (CP), and the e2 allele has been associated with worse neurological outcome with congenital heart dis- ease. This study was done to test the hypothesis that the APOE genotype is associated with outcome among neonates who survive after ...
Apolipoprotein E Genotype Predicts 24-Month Bayley Scales Infant Development Score ROBERT O. WRIGHT, HOWARD HU, EDWIN K. SILVERMAN, SHIRNG W. TSAIH, JOEL SCHWARTZ, DAVID BELLINGER, EDUARDO PALAZUELOS, SCOTT T. WEISS, AND MAURICIO HERNANDEZ-AVILA Departments of Pediatrics [R.O.W.] and ...
determine whether brain activation patterns associated with working memory differ as a function of apolipoprotein E (APOE) genotype in cognitively intact adults... HA Wishart,AJ Saykin,LA Rabin,... - 《American Journal of Psychiatry》 被引量: 237发表: 2006年 Impact of apolipoprotein E ε4 and...
Patients with AD and DUE did not differ in sex, risk factors, apolipoprotein E genotype, neuropsychological features, or neurological features. Hippocampal ... HA Crystal,D Dickson,P Davies,... - 《Arch Neurol》 被引量: 274发表: 2000年 Apolipoprotein E Genotypes: Relationship to Cognitive Funct...
(https://www.23andme.com), which includesAPOEgenotype analysis, has attained FDA approval. The fact that our apoE isotyping method does not require the isolation and analysis of DNA simplifies the requirements for analysis (e.g. informed consent), being potentially applicable to different mostly ...
Science 211: 1437- 1438 Noguchi S, Murakami K, Yamada N (1993): Apolipoprotein E genotype and Alzheimer's disease. Lancet 342:737 Noma A, Okat~e H, Netsu-Nakayama K, Ueno Y, Shinohara H (1979): Improved method for simultaneous determination of cholesterol in high- and low-density ...
or neuropsychological test scores among the three subject groups, whole brain atrophy rates were significantly greater in the epsilon4 homozygote group than in noncarriers and were significantly correlated with epsilon4 gene dose (i.e., the number of epsilon4 alleles in a person's APOE genotype)...
The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo B in
The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo B in