In normal controls, the molecular weights of apo(a) isoforms were inversely correlated with plasma Lp(a) levels, and the same tendency was found in patients who were undergoing hemodialysis and/or who had diabetes mellitus. We assumed the differences in apo(a) phenotypes detectable with our ...
Live cell images of the co-culture clearly demonstrate a disruption to the normal integration of trophoblast into endothelial tubular structures in the presence of TNF-α. The protective effect conferred by pre-incubation of endothelial cells with apoA-I against TNF-α is also clearly visible. ...
Determination by the SRID Method of Normal Values of Serum Apolipoproteins (A-I, A-II, B, C-II, C-III, and E) in Normolipidemic Healthy Japanese Subjects The normal levels of apolipoproteins in Japanese were investigated by the single radial immunodiffusion method. No differences were seen...
(Namba and Ikeda, 1991), and subsequently, in 1993,APOEε4 allele was reported as a risk factor for AD (Corder et al., 1993). TheAPOEε4 allelic frequency is around 15% in the normal population but increases to 40% in patients with AD (Nakamura et al., 2018;Strittmatter et al., ...
The distribution of Lp(a) levels in normal subjects was skewed to the left with 97% having levels below 300 mg/ L. A subpopulation with increased Lp(a) levels (13鈥 42%) could be detected in all groups with renal disease, and increased mean serum Lp(a) levels were found in patients...
Levels of Apolipoprotein A-I and B and lipid profile in 60 Coronary Heart Disease patients admitted with first episode of coronary heart disease in ICCU were compared with 60 healthy apparently normal age, sex matched individuals. Results: It was observed that levels of apolipoprotein A-I and ...
Apolipoprotein (apo) A-I is the most abundant apolipoprotein constituent of high density lipoproteins (HDLs)1. In normal human plasma 5–10% of the total apoA-I exists in a lipid-free or lipid-poor form that accepts cholesterol from peripheral cells expressing the ATP-binding cassette transporte...
The risk of death from coronary heart disease (CHD) is substantially increased in diabetic nephropathy compared with normal subjects or diabetes without nephropathy. I tried to define abnormal plasma lipoproteins profiles contributing to the increased CHD risk in diabetic nephropathy. This study included...
Characterization and quantitation of apolipoproteins A-I and E of normal and cholesterol-fed guinea pigs. J Lipid Res. 1982 May; 23 (4):531–542. [ PubMed ]Guo LSS, Hamilton RL, Kane PJ, Fielding CJ, Chen GC. Characterization and quantitation of apolipoproteins A-I and E of normal ...
Lp(a) levels >50 mg/dl are highly prevalent (20% of the general population) and are overrepresented in patients with CVD and aortic stenosis. These data support the notion that Lp(a) should be a target of therapy for CVD event reduction and to reduce progression of aortic stenosis. ...