cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum...
Apo B and cholesterol values were in the normal range in women investigated after two years of steroid intake. An inverse trend was observed for plasma triglycerides, which showed a mean increase of 29% ( p < 0.01) after three months of steroid intake, and then stayed elevated without ...
Reduced Apolipoprotein E-Rich High-Density Lipoprotein Level at Birth Is Restored to the Normal Range in Patients with Familial Hypercholesterolemia in the First Year of LifeConclusion: ApoE-rich HDL level is low at birth in FH children and increases to the normal level in the first year of ...
Although in a normal range, triglycerides were also higher in FH (P < 0.05). Furthermore, compared to controls, higher HDL-triglycerides and HDL-apoE concentrations were observed in FH patients (P < 0.05). Plasma apoA-I concentration and pool size, as well as HDL-cholesterol level, showed...
The plasma HDL-C (53 ± 15 mg/dL), LDL-C (137 ± 36 mg/dL), and TG (119 [86; 167] mg/dL) levels were in the normal range (Table 2). During the 5-year follow-up (IQR 25–62 months, 262/307 patients (85.3%) until the 5th visit), 115 participants (37.5%) ...
75% of Apo A in HDL is Apo AI. Levels of Apo AI are inversely related to the risk of coronary heart disease. Apo AI is also thought to activate LCAT (lecithin cholesterol acyl tranferase). In normal plasma, Apo AI levels range from 90-130 mg per 100 ml....
Moreover, the serum concentrations of these HDL constituents were considered to be at the lower border of the normal range in the proband with the mutant, who was initially identified in our screening program (11-7).However, the HDL-C, apo A-I, and apo A-I1 concentrations were normal ...
Briefly, 10 ~1 of VLDL-rich fraction was separated from 180 ~zl of serum by ultracentrifugation for 38 min at 100,000 rpm using a Beckman TLA-100 rotor. Ampholine mixtures of 1.4~ pH range 5-8 and 0.6~ pH range 3-10 were used in the first-dimensional disc gel. After the two-...
Background:Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one...
The diagnosis is based on elevated TG levels with cholesterol levels that are usually in the normal range [17]. ApoB levels are usually normal as well as LDL-C but carried in smaller, denser particles (Table 1); HDL-C can be markedly reduced despite normal apoA-I. The apoB/apoA-I ...