The elevation was more prevalent but less extreme than that reported in patients with cardiovascular disease. Density gradient centrifugation studies of plasma from cancer patients revealed the presence of apolipoprotein(a) at a density of 1.085 g/ml in the region where mRNA-containing proteolipids, ...
ROS-associated chemotherapy related ApoA-I oxidation leads to elevation of peripheral levels of tumor necrosis factor- (TNF-) that can cross the blood-brain barrier (BBB) causing a signaling cascade that can contribute to neuronal death, likely a contributor to what patients refer to as "chemo...
During the first 12 months, this elevation was relatively Y.-M. Kuo et al.: Apolipoprotein E and Amyloid Deposition 433 Fig. 1. Quantification of apolipoprotein E (apoE) and cholesterol in brain and of amyloid-  (A) peptides in plasma and brain. Concentra- tions for tg2576 (...
Lipoprotein(a) [Lp(a)] has been considered to be a predictor of premature coronary heart disease and other cardiovascular diseases. Lp(a) levels are largely genetically determined, but the detailed mechanism of Lp(a) elevation is uncertain. We examined the association between Lp(a) levels and...
Methods: In this retrospective study, the authors reviewed medical records of 107 consecutive patients diagnosed with acute coronary syndrome (ACS) without ST-segment elevation admitted within a one-year period and who had undergone coro... RA Penalva,MDO Huoya,LCL Correia,... - 《Arquivos Bras...
The elevation in 3/4 genotype frequencies was also found in premenopausal group (21.6%) and in patients with advanced tumor (77.7%). Body mass index (BMI) and familial incidence did not show association with APOE genotype. The results suggest the influence of APOE genotype on development of ...
Elevation of artherogenic lipoproteins caused by impaired catabolism. JAMA 265: 78–83 Article CAS Google Scholar Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM 1985 Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the ...
The elevation of LPS level in chlorpyrifos treated mice is a reason behind the higher level of gut epithelium breakdown which was demonstrated by gut permeability assay. In addition, systemic inflammation could induce inflammation in insulin-responsive tissues which consequently caused insulin resistance ...
An elevated preoperative value of CA 19-9 was found not to be prognostic of survival, while its continual elevation in the postoperative setting was a significant indicator of poor outcome (Hata et al, 2012). Carbohydrate Antigen 19-9 is frequently elevated in benign conditions and more so in...
ApoA-I-Induced Elevation in PON Activity. The level of secreted arylesterase activity was significantly increased in the presence of ApoA-I (n=5). These results suggest that PON activity was dependent on the assembly of nascent HDL. However, that lipid-free ApoA-I may interact with secreted...