Defects in APOA1 are a cause of the low HDL levels observed in high density lipoprotein deficiency type 1 (HDLD1) [MIM:205400]; also known as analphalipoproteinemia or Tangier disease (TGD). HDLD1 is a recessive disorder characterized by the absence of plasma HDL, accumulation of choleste...
Results: Apo B/A1 levels of T2DM patients combined with VitD deficiency was significantly higher than that of non-VitD deficiency patients, and the VitD levels of patients with high apo B/A1 was significantly lower than that patients with low apo B/A1 (all P< 0.001). Spearman correlation...
Immuno-assay on an automated random immuno-analyser confirmed the correlation between Apo-A1 concentrations and JAK2 V617F percentages, and showed that serum Apo-A1 assay allowed the specific discrimination of PV patients with high levels of mutated alleles (75%). These data suggest that Apo-A1 ...
Recent studies have reported of an association between high serum apolipoprotein A1 (APOA1) levels and favorable prognosis in several malignancies, while the significance of apolipoprotein B (APOB) in cancer is less well-known. In this study, we analyzed the correlation between serum APOA1 and AP...
Apolipoprotein A-I (APOA1) is the major protein component of high-densitylipoproteins(HDLs).APOA1is an activator of theenzymelecithin-cholesterol acyltransferase (LCAT) and a key component ofreverse cholesterol transport. Moreover, Calabresi et al.[1]showed that carriers of the A1-Milano mutation...
Apolipoprotein A1 (apoA1) is a component of the high density lipoproteins (HDL) that regulates the transport of cholesterol between the liver and peripheral cells and modulates the removal of any excess of cholesterol from membranes. Any variation in apoA1 composition may modify the plasma lipid ...
Apolipoprotein A1 Apolipoprotein A-I PDB rendering based on 1av1. Available structures: 1av1, 1gw3, 1gw4, 2a01 Identifiers Symbol(s) APOA1; MGC117399 External
12–14 Higher levels of low density lipoprotein cholesterol (LDL) and apolipoprotein B:A1 have been associated with an increased risk of subsequent ALS, with temporal changes in the lipid biomarker profile observed in the decade prior to diagnosis.15 Mendelian randomisation studies have also provided...
Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes. The apolipoprotein gene cluster (APOA1/C3/A4/A5) was recently associated with triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) in non-di.....
Different apolipoprotein E, apolipoprotein A1 and prostaglandin-H2 D-isomerase levels in cerebrospinal fluid of schizophrenia patients and healthy controls. Objectives. To identify proteins differentially expressed in schizophrenia patients, we collected 50 碌l cerebrospinal fluid from 17 first-episode schizoph...