Ongoing research continues to expose additional activities for these effector proteins and has revealed unanticipated functions of the antiviral response.Anthony J SadlerBryan R G WilliamsSamuel, C. E. 2001 Antiviral actions of interferons. Clin. Microbiol. Rev. 14, 778-809. (doi:10.1128/CMR.14.4...
Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Considerable progress has been made in the understanding of the molecular biology of the human interferon system. The genes encoding the interferons, their... CE Samuel - 《...
Antiviral Actions of Interferons Tremendous progress has been made in understanding the molecular basis of the antiviral actions of interferons (IFNs), as well as strategies evolved by vir... CE Samuel - 《Clinical Microbiology Reviews》 被引量: 5104发表: 2001年 Cell type-specific involvement of...
Antiviral actions of interferons 2001, Clinical Microbiology Reviews SOCS proteins: Negative regulators of cytokine signaling 2001, Stem Cells View all citing articles on Scopus * This study was supported by funds from the California Breast Cancer Research Program of the University of California (1KB-...
select article Antiviral activities of type I interferons to SARS-CoV-2 infection Research articleFull text access Antiviral activities of type I interferons to SARS-CoV-2 infection Emily Mantlo, Natalya Bukreyeva, Junki Maruyama, Slobodan Paessler, Cheng Huang ...
E. Interferons and their actions. Annu. Rev. Biochem. 56, 727–777 (1987) Article CAS Google Scholar De Maeyer, E. & De Maeyer-Guignard, J. Interferons and Other Regulatory Cytokines (John Wiley and Sons, New York, 1988) Google Scholar Vilcek, J. & Sen, G. S. in Fields ...
The host response to viral infection includes the induction of type I interferons and the subsequent upregulation of hundreds of interferon-stimulated genes. Ubiquitin-like protein ISG15 is an interferon-induced protein that has been implicated as a central player in the host antiviral response. Over...
Of importance, a crucial role during the early phases of infection is made by the antiviral innate immune response, including complement systems, interferons (IFN), chemokines, and immune cells (e.g.,macrophages) whose role mainly consist in limiting the viral propagation via modulating cytokine pr...
Transcriptional activation of human Ifnb1 requires the concerted actions of virus-activated and constitutive transcription factors to assemble an enhanceosome complex at a nucleosome-free region upstream of the transcriptional start site (TSS), which is obscured by a well-positioned nucleosome (Thanos ...
(IEC) and cytokine-mediated re-growth of healthy IEC. Here we show that one of the most conspicuous impacts of activated IEL on IEC is the functional upregulation of antiviral interferon (IFN)-responsive genes, mediated by the collective actions of IFNs with other cytokines. Indeed, IEL ...