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(Ed.), Interferon, General and Applied Aspects, vol. 1. Elsevier, Amsterdam, p. 189.Grossberg, S. E., Sedmak, J.J.: The assay of interferons. In: The Interferons and Their Inducers, edited by Billiau, A., Fin- ter, N., (3rd edition) North HolIand Publishing Co. 1984. pp 189...
On the 50th anniversary of the discovery of interferon (IFN), we offer a perspective from more than 100,000 published papers, highlighting initial pivotal discoveries and more recent findings of conceptual importance. This covers the mechanisms of IFN induction, the cellular actions of IFN and IFN...
Interferons and their Actions The interferon system is the first line of defense against viral infection in mammals. This system is designed to block the spread of virus infection in th... Pestka,S,Langer,... - 《Annu.rev.biochem》 被引量: 3148发表: 1987年 ...
Type I IFNs are implicated in different autoimmune and inflammatory conditions, although their role in each condition varies. Some autoimmune diseases are improved by the biological effects of type I IFNs, whereas others benefit from type I IFN inhibition. Abstract Interferon-α (IFNα) and IFNβ...
Pellegrino MA, Ng AK, Russo C, Ferrone S (1982) Heterogeneous distribution of determinants defined by monoclonal antibodies on HLA-A and B antigen bearing molecules. Transplantation 34: 18 Google Scholar Pestka S, Langer JA, Zoon KC, Samuel CE (1987) Interferons and their actions. Annu Rev...
Interferon’s (α and β), produced both by recombinant DNA technology as well as purified from natural sources, have been shown to be efficacious in treating certain cancers and viral diseases. Studies with γ-interferon have more recently been undertaken, and thus definition of their clinical ...
These advances highlight the context-specific actions of type I IFNs and clarify the multiple points at which they are integrated into both innate and adaptive immunity. 展开 关键词: cervical cancer papillomavirus public health vaccine technology DOI: 10.1016/j.immuni.2006.08.007 被引量: 1958 ...
Apo2L/TRAIL and Bcl-2鈥搑elated proteins regulate type I interferon鈥搃nduced apoptosis in multiple myeloma It has been reported that interferons (IFNs) may have antitumor activity in multiple myeloma (MM). The mechanism for their effect on MM, however, remains e... C Quan,B Gong,AS Mahm...
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