Macrophages from thymectomised donors were partially deficient in their capacity to activate naive or immune T-cells in vitro but were nevertheless capable of emitting a significant immunogenic signal. These results suggest partial, but not absolute T-cell regulation of the immunogenic function(s) ...
Fruth U, Solioz N, Louis JA (1993) Leishmania major interferes with antigen presentation by infected macrophages . J Immunol 150 : 1857–1864Fruth U, Solioz N, Louis JA. Leishmania major interferes with antigen presentation by infected macrophages. J Immunol. 1993; 150 :1857–1864....
Phosphoantigen Presentation by Macrophages to Mycobacterium tuberculosis-Reactive Vγ9Vδ2+ T Cells: Modulation by Chloroquine Vγ9Vδ2+ T cells (γδ T cells) are activated by Mycobacterium tuberculosis and recognize mycobacterial nonpeptide phosphoantigens. The role of... Roxana,E.,Rojas,... ...
These results demonstrate that a macrophage tumor cell line can be induced to present antigen and provides for large numbers of readily available, homogeneous macrophages for studying the cellular biochemical requirements for antigen processing and presentation. 展开 ...
Antigen Processing and Presentation by MHCs Apoptosis Pathways Death Receptor Pathway APRIL Pathway B-Cell Development Pathway B-Cell Receptor Complex BMP 通路 Bone Biology Pathways Cancer Biology Pathways Cancer Immunoediting CCR5...
1、Chapter 11 Antigen Presenting Cells and Antigen presentation I. APC (antigen presenting cells)Professional APCs(DCs, macrophages, B cells)Non-professional APCsII. Ags Processing and presenting pathwayMHC class I pathwayMHC class II pathwayCross presentationNon-classical antigen presentation pathwayC 2...
文稿10.上课定稿antigen presentation.pptx,Antigen presentation Antigen presentationDefinitionAntigen-presenting cellsAntigen processing and presentation Definition of antigen presentation The process by which certain cells in the body (antigen-presenting
Here we find that genetic depletion of Npm1 restores MHC-mediated antigen presentation in tumor cells and effectively induces CD8+ T cell infiltration into the TME, suggesting that NPM1 promotes tumor progression and supports tumor immune evasion. Mechanistically, NPM1 inhibits MHC expression by ...
Antigen presentation by Theileria annulata‐infected macrophages and production of continuously grow... Theileria annulata , a protozoan parasite of cattle, infects major histocompatibility complex (MHC) class II+ cells, particularly macrophages, and transfor... EJ Glass,RL Spooner - 《European Journal...
Autoantibody produced by the initiating clone was not sufficient to drive the autoreactive response. Subsequent epitope spreading depended on antigen presentation and was compartmentalized by major histocompatibility complex (MHC). B cells carrying two MHC haplotypes could bridge the MHC barrier between B...