Steptoe RJ, McMenamin PG, Holt PG (2000) Resident tissue macrophages within the normal rat iris lack immunosuppressive activity and are effective antigen-presenting cells. Ocul Immunol Inflamm 8(3):177–187 Sep View ArticleSteptoe RJ,McMenamin PG,Holt PG.Resident tissue macrophages within the ...
Expression of α7 nicotinic acetylcholine receptors (nAChRs) on antigen presenting cells (APCs), such as macrophages and dendritic cells, is now well established. We have shown that GTS-21, a selective α7 nAChR agonist, downregulates APC-dependent CD4+ T cell differentiation into regulatory T ce...
Macrophages are A、Long-lived B、short-lived C、NOT antigen presenting cells D、differentiated from T cells E、differentiated from B cells 点击查看答案 你可能感兴趣的试题 判断题《药品管理法》2019年修订版规定,药品监督管理部门根据监督管理的需要,可以对药品质量进行抽查检验。抽查检验应当按照规定抽样,...
Dendritic cells (DC) were found to be more efficient than macrophages (MO) in activating T cell responses to Staphylococcal enterotoxin B (SEB) using the hanging drop techniques and DC as antigen presenting cells (APC). When superantigen was presented via DC, the activation of T cells was no...
To define the phenotype and location of antigen-presenting cells (APCs) in normal donor human corneas, and to assess the response of APC to herpes simplex virus type 1 (HSV-1) infection.Donor human corneal tissue was analyzed by fluorescence confocal microscopy and flow cytometry to determine ...
Because antigen-presenting/accessory cells (APCs) produce cytokines that can modulate the development of Th1 and Th2 phenotypes, we addressed whether APCs from SJL mice were genetically programmed for elevated expression of the Th1-promoting cytokine, IL-12. Activated peritoneal macrophages (Mphi; i....
et al. Inflammation conditions mature dendritic cells to retain the capacity to present new antigens but with altered cytokine secretion function. J. Immunol. 193, 3851–3859 (2014). Article CAS PubMed Google Scholar Spörri, R. & Reis e Sousa, C. Inflammatory mediators are insufficient ...
Subclustering of immune cells resulted in eight immune cell clusters, including T and B cells, granulocytes, and antigen-presenting cells (Figs.2DandS2C). Interestingly, CD4 and CD8 T cells from healthy samples (hTcells) formed a distinct cluster, adjacent to CD4 (tCD4) and CD8 T cells (...
Here, we report that, in areas of disturbed blood flow, aortic endothelial cells permanently and intimately associate with a population of specialized macrophages. These macrophages are recruited at birth from the closing ductus arteriosus and share the luminal surface with the endothelium, becoming ...
In many malignancies, both innate and adaptive immune cells play a role in the tumor microenvironment, with communication between natural killer (NK) cells, antigen presenting cells (APCs) such as macrophages and dendritic cells (DC), and lymphocytes allowing for effective tumor control11. ...