Automated antibody structure prediction using Accelrys tools: Results and best practices. Proteins: Structure, Function, and Bioinformatics. 2014 Aug 1; 82(8):1583-98.Fasnacht M et al. Automated antibody structure prediction using Accelrys tools: results and best practices. Proteins 2014; 8: 1583-...
Since the rank of the best prediction was at most in the top three for more than 70% of proteins and never exceeded five, ElliPro is considered a useful research tool for identifying antibody epitopes in protein antigens. ElliPro is available at urlhttp://tools.immuneepitope.org/tools/...
As the number of structures of antibody-protein complexes grows, further interest in prediction methods using 3D structure is anticipated. This work aims to establish a benchmark for 3D structure-based epitope prediction methods. Results Two B-cell epitope benchmark datasets inferred from the 3D ...
SAbPred: a structure-based antibody prediction server 来自 Semantic Scholar 喜欢 0 阅读量: 58 作者:J Dunbar,K Krawczyk,J Leem,C Marks,CM Deane 摘要: SAbPred is a server that makes predictions of the properties of antibodies focusing on their structures. Antibody informatics tools can help ...
SAbPred a structure-based antibody prediction server.SAbPred抗体预测小服务器 文档格式: .pdf 文档大小: 182.84K 文档页数: 5页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: 论文--期刊/会议论文 文档标签: SAbPredastructure-basedantibodypredictionserver46SAbPred抗体预测小服务器 ...
performed the model parameterization and prediction of experimental SPR curves for an untested three-antigen triangular structure for three independent replicates with different corresponding bound structure amounts, whereas the experimental test data obtained by A.S. and I.S. were withheld until the ...
AlphaFold2 protein structure prediction: Implications for drug discovery The drug discovery process involves designing compounds to selectively interact with their targets. The majority of therapeutic targets for low molecular weight (small molecule) drugs are proteins. The outstanding accuracy with which re...
including protein structure prediction14, and drug discovery and design15,16,17,18,19,20,21. Existing ML-driven antibody optimization has shown promising results in designing antibodies with improved binding characteristics against a target and that antibody binding can be learned from only sequence da...
Engineering the active site of glycosyltransferases has provided tools for introducing chemically modified sugar substrates [26]. Native IgGs were converted to a homogenous G0f glycoform population by using β-1,4-galactosidase from Streptococcus pneumoniae. The resulting antibody was modified with a ...
Nanobody-based products as research and diagnostic tools Since the serendipitous discovery 20 years ago of bona fide camelid heavy-chain antibodies, their single-domain antigen-binding fragments, known as VHHs or... TD Meyer,S Muyldermans,A Depicker - 《Trends in Biotechnology》 被引量: 263...