The current predictive methods for proteinprotein binding affinity usually fail to predict the binding affinity of an antibodyprotein antigen complex with a comparable level of accuracy. Here, new models specific for antibodyantigen binding affinity prediction are developed according to the different types...
First, the interactions between molecules such as CD4 (Chapter 9) and major histocompatibility complex (MHC) class II (Chapter 5), which are not clonally distributed, are often described as nonspecific, meaning “not specific for an antigen under consideration.” Second, for many purposes ...
Beneficial from the recent breakthroughs in deep learning for antibody structure prediction, we propose a novel neural network architecture to predict antibody-antigen interaction. We first introduce AbAgIPA: an antibody structure prediction network to obtain the antibody backbone structure, where the stru...
Machine learning (ML) is a key technology for accurate prediction of antibody–antigen binding. Two orthogonal problems hinder the application of ML to antibody-specificity prediction and the benchmarking thereof: the lack of a unified ML formalization of immunological antibody-specificity prediction prob...
antibodylanguage-modelantibody-structure-prediction UpdatedAug 26, 2024 Python Template-based assembly of proteomics short reads for de novo antibody sequencing and repertoire profiling sequencingantibodymass-spectrometry UpdatedOct 15, 2024 C# Material to run the HADDOCK antibody-antigen modelling protocol ...
Viruses and bacteria commonly exhibit spatial repetition of the surface molecules that directly interface with the host immune system. However, the complex interaction of patterned surfaces with immune molecules containing multiple binding domains is poo
(MAE). To better evaluate our model, we also tested other well-known structure-based antigen–antibody affinity prediction model (e.g. CSM-AB and AREA-AFFINITY). We input the 26 complex structures from the independent set into their online prediction website and manually calculated the R, R2...
Antigen–Antibody Interface Residue Predictiondoi:10.1007/978-1-4419-9863-7_100049B Cell Epitope PredictionWerner DubitzkySpringer New York
Description: The HM48-1 monoclonal antibody reacts with the mouse CD48 antigen; also known as BCM1, Blast-1 (human), and OX-45 (rat). CD48, a member of the SLAM family and Ig superfamily, is a 45 kDa GPI-linked glycoprotein expressed on the majority of hematopoietic cells. Recent ...
蛋白别名: B-cell activation marker; BCM1 surface antigen; BLAST-1; CD48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48d; HM48-1; MRC OX-45 surface antigen; sCD 48; sCD48; sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAM...