However, only 12.3% of them had a titer 鈮 1/320. The sensitivity of the ANA in patients with SLE as assessed by IFA was more than 98%. Nuclear membrane and DFS70 patterns are not specific to any connective tissue disease and they can be detected positive in rheumatoid arthritis and in...
(CDC) criteria (http://www.cdc.gov/ncphi/disss/nndss/casedef/ehrlichiosis_2008.htm) by either seroconversion, a 4-fold increase in A phagocytophilum IgG antibody titer in acute and convalescent sera, or a positive PCR result for both A phagocytophilum rrs and groEL confirmed by direct ...
phagocytophilum of at least 80; (2) a fourfold increase or decrease in the antibody titer within 4 weeks; (3) a positive PCR test result using specific A. phagocytophilum primers; or (4) isolation of A. phagocytophilum from blood.22 These criteria could also be applied to ...
D.Canbefoundinlowtitersinhealthy individuals 2 Anti-NuclearAntibody(ANA) E.Hightiters(>1:320)ishighlysuggestiveofan autoimmunedisease F.Lowornegativeresultdoesnotruleout autoimmunedisease G.Manypatientswithdifferentkindsof autoimmunediseaseswillhavegenericANA’s ...
(fever and seroconversion with a 4-fold change in serum antibody titer to A. phagocyt- ophilum), one was a probable HGA case (fever and acute and convalescent serum samples with unchanging IFA titer), two patients had a possible HGA infection (serum samples with a titer of ≥ 1:128...
Objective: It is important to choose the correct screening titer in immunoflourescent assay for ANA. Recently, 1:160 titer is used worldwide, particularly after the suggestion of CDC (Centers for Disease Control and Prevention) and WHO (World Health Organisation). In our country, 1:100 is the...
14 patients showed double-positivity by PCR and IFA tests. Twenty-four patients out of 139 had an IgM titer of 1:16 or higher, or an IgG titer of 1:80 or higher in the acute phase, but there was no increase in antibody levels in the recovery phase. In addition, when PCR forAnaplas...
Immunodominant epitope: The epitope on a molecule that induces a dominant, or most intense, immune response. The immunodominant epitope may elicit, for example, the greatest antibody titer during infection or immunization, as measured by, for example, the fraction of reactivity attributable to a cer...
Use of Computer-Aided Immunofluorescence Microscopy (CAIFM) for Interpretation of Antinuclear Antibody (ANA) Pattern and Titerantinuclear antibodyautoimmune diseasedigital pathologycomputer-aided immunofluorescence microscopyThe assessment of antinuclear antibodies (ANA) by indirect immunofluorescence (IFA) allows ...
For other systemic and nonsystemic autoimmune diseases sensitivity and specificity of COBAS-ANA were similar or higher than that of 1:160 IFA-ANA titer.ConclusionSensitivity and specificity of COBAS Core ANA-EIA for SLE and other systemic and nonsystemic autoimmune diseases, together with performance...