白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴...
白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)和急性髓系白血病(acute ...
2. 2024ASH #1473 Outcomes of Newly Diagnosed Acute Myeloid Leukemia Patients between 65-75 Years and Treated with Intensive Induction Chemotherapy Versus Hypomethylating Agents and Venetoclax: A Propensity Score Adjusted Cohort Stud...
属于急性白血病的一种。白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)...
白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)和急性髓系白血病(acute...
急性白血病包括急性髓系白血病(Acute myelocytic leukemia,AML)和急性淋巴细胞白血病(Acute lymphoblastic leukemia,ALL),需要在不同的治疗阶段(治疗方案不同),达成不同的阶段目标。 其中,高度异质性的急性淋巴细胞白血病(ALL)的生物学特征多样,临床异质性很强,该病主要起源于淋巴细胞的B系(B-ALL)或T系细胞(T-ALL)...
Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options, depending solely on cytarabine + anthracycline (7 + 3) intensive chemotherapy and hypomethylating agents. Allogeneic stem cell transplantation (Allo
Learn about ONUREG® (azacitidine), a continued treatment option for acute myeloid leukemia (AML) in first remission. See Safety Information and Full Prescribing Information.
631 Accesses Explore all metrics Abstract An increasing number of older patients with acute myeloid leukemia (AML) are offered an allogeneic hematopoietic stem cell transplantation (allo-HSCT). Normally, older patients have older matched related donors (MRD). Matched unrelated donors (MUD) are an ...
The overexpression of the ecotropic viral integration site-1 gene (EVI1/MECOM) marks the most lethal acute myeloid leukemia (AML) subgroup carrying chromosome 3q26 abnormalities. By taking advantage of the intersectionality of high-throughput cell-based and gene expression screens selective and pan-...