白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴...
白血病(leukemia)是起源于造血干细胞的恶性克隆性疾病,受累细胞(白血病细胞)出现增殖失控、分化障碍、凋亡受阻,大量蓄积于骨髓和其他造血组织,从而抑制骨髓正常造血功能并浸润淋巴结、肝、脾等组织器官。根据主要受累的细胞系列可将急性白血病分为急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)和急性髓系白血病(acute ...
但相比前者,T-ALL的恶性程度更高,预后较差,且复发率高。在成人T-ALL 患者中,仅有40%的患者生存期超过5年。 而急性髓系白血病(acute myeloid leukemia,AML)是成人中最常见的急性白血病类型,约占成人白血病的70%,并且发病率随年龄增加...
ISAL 2019 | The role of minimal residual disease guided treatment in acute myeloid leukemia Add bookmark Prognostic factors in patients with NPM1-mutated AML: Analysis from the AML17 and AML19 trials Congresses view more Add bookmark Tamibarotene + Ven + Aza combination in patients with AML:...
治疗选择中危组Allo及AutoVSCTP0.001AlloVSAutoP0.05CornelissenJJ,Leukemia,,29(5):517–525.AML的治疗进展医学知识讲解第39页 治疗选择alloHSCT是年纪40-60岁、中危及高危患者首选治疗方式,而autoHSCT仍被认为是中危AML一个治疗选择。CornelissenJJ,Leukemia,,29(5):517–525.AML的治疗进展医学知识讲解第40页 ...
1) acute myeloid leukemia(AML) 急性髓细胞性白血病(AML)1. Aim:To establish a real-time PCR technique for detection and quantify of Elf-1 gene expression and to investigate the expression level of Elf-1 gene in patients with acute myeloid leukemia(AML). 目的:建立实时定量PCR检测Elf-1基因...
1. Issa GC, Cuglievan B, DiNardo CD, et al. Early results of the Phase I/II study investigating the all-oral combination of the Menin inhibitor revumenib (SNDX-5613) with decitabine/cedazuridine (ASTX727) and venetoclax in acute myeloid leukemia (SAVE).Blood. 2023;142 (suppl 1...
Context:There is a paucity of contemporary population-based data on acute promyelocytic leukemia (APL) in the United States (US).Objective:To determine epidemiology of APL admissions and their predictors of mortality.Design:Retrospective analysis utilizing National Inpatient Sample to identify APL ...
Learn about ONUREG® (azacitidine), a continued treatment option for acute myeloid leukemia (AML) in first remission. See Safety Information and Full Prescribing Information.
5NPM1mut·临床特征MutationofNPM1andFLT3GenesinAcuteMyeloidLeukemiaandTheirAssociationwithClinicalandImmunophenotypicFeatures6NPM1mut·细胞形态学7NPM1mut·免疫表型NPM1基因突变的急性髓系白血病免疫表型研究8鉴别点•发病年龄:NPM1m+AML患者发病年龄高于APL患者(54yvs34y)•WBC、PLT计数:NPM1m+AML患者计数高于...