Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. AML usually begins in cells that turn into white blood cells but can also start in other blood-forming cells. When ...
20. Singh A, Locke SC, Wolf SP, et al. The relationship between emotional well-being and understanding of prognosis in patients with acute myeloid leukemia (AML). Support Care Cancer. 2022;30:897–906. doi: 10.1007/s00520-021-06499-w. 21....
innovative immunomodulatory agents, all aimed at striking a delicate balance between averting GvHD and safeguarding the beneficial graft-versus-leukemia (GvL) effects (Malard et al.2023; Choi et al.2010; Cooke et al.2017). Splenomegaly is associated with a poor prognosis and primary graft failure...
In conclusion, addition of a third drug (etoposide) does not seem to significantly improve the poor prognosis of MDS-AML patients.doi:10.3109/10428190009148402Taylor & FrancisLeukemia & LymphomaLatagliata R,Breccia M,Pulsoni A. Acute myeloblastic leukemia secondary to myelodysplasia (MDS-AML):a ...
Leukemia 2011; 25: 110–120. 7 Kulasekararaj AG, Smith AE, Mian SA, Krishnamurthy P, Mohamedali AM, Lea NC et al. TP53 mutations are restricted predominantly to 5qÀ syndrome and myelodysplastic syndrome patients with complex cytogenetics, and correlate with adverse prognosis. Blood 2011; ...
The present invention provides novel methods and compositions for acute myeloid leukemia (AML) in the diagnosis, prognosis and treatment. 本发明还提供了鉴别抗AML试剂的方法. The present invention also provides a method of identifying an anti-AML agent....
[3]E M Heath,S M Chan,M D Minden,T Murphy,L I Shlush,A D Schimmer. Biological and clinical consequences of NPM1 mutations in AML[J]. Leukemia,2017,31(20): [4]DUPLOYEZ N, WILLEKENS C, MARCEAU-RENAUT A, et al. 2015. Pr...
Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options, depending solely on cytarabine + anthracycline (7 + 3) intensive chemotherapy and hypomethylating agents. Allogeneic stem cell transplantation (Allo
Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis Blood, 68 (1986), pp. 1242-1249 View PDFView articleView in ScopusGoogle Scholar 17 CD Bloomfield, C Shuma, L Regal, et al. Long-term survival of patients with acute myeloid leukemia...
Prognosis of acute myeloid leukemia (AML) patients depends on patient-related features, disease manifestations at the time of presentation, and intrinsic disease-related genetic features, such as cytogenetic abnormalities and driver mutations. Prognostic stratification also depends on the therapeutic strategy...