Related to amide:Amide hydrolysis,Sodium amide amide amide(ămˈīd), organic compound formed by reaction of an acid chloride, acid anhydride, or ester with an amine. Under strong acidic conditions an amide can be hydrolyzed to yield an amine and a carboxylic acid. The reverse of this pro...
amide formation, amide hydrolysisThe dimethylene compounds (II) and (IV), when treated with nitriles (Ia) and (Ia)/(Ib) under acidic conditions undergo an intramolecular cyclization and a subsequent Ritter reaction affording the amides (III), and (Va)/(Vb), respectively.doi:10.1002/chin....
Dimethyl sulphoxide proved to be a good solvent for the diaxial cleavage of epoxides by alkali, while hydrolysis in the same solvent under acidic conditions led to the diaxial glycol 7 from the trans epoxide 3, and to the di... G Berti,B Macchia,F Macchia - 《Tetrahedron》 被引量: 63...
(R)-1-(3-cyanophenyl)ethylamine and (R)-l-(4-cyanophenyl)ethylamine can not be prepared by acidic or alkaline hydrolysis of the corresponding (R)-N-acetylamides (the left over enantiomer from the racemate under catalysis of the acylase from Rhodococcus equi Ac6) because this treatment resu...
For the model reaction of glycylglycine hydrolysis, ZrO2 was found to work as an effective catalyst and afforded glycine in up to 97%-C under the optimum conditions, while acidic oxides and basic oxides were inferior to ZrO2. The characterization using N2 physisorption, XRD, NH3-TPD, and CO2...
Hydrolysis of the tert-butyl ester intermediate (3) in dichloromethane with trifluoroacetic acid (TFA) followed by repeated lyophilization form diluted HCl solution afforded the desired final product 1,4,7,10-tetraazacyclodoecane-1,7-di(acetic acid)-4,10-di(N-butylacetamide) (DO2A2MnBu) (4)...
A methyl ester is converted into a carboxylic acid upon acidic hydrolysis. The hydrolysis of a methyl ester under acidic conditions yields a... Learn more about this topic: Amide | Structure, Functional Group Bond & Examples from Chapter 5/ Lesson 9 ...
Amide bonds are highly stable and are considered practically irreversible under typical ambient conditions (rate constant for hydrolysis of amides7 are of the order of 10−11 s−1), including in acidic or basic aqueous solutions8, and are thermally robust9. Furthermore, amides are formed ...
Amides are important intermediates in organic chemistry and the pharmaceutical industry, but their low reactivity requires catalysts and/or severe reaction conditions for esterification. Here, a novel approach was devised to convert amides into esters without the use of transition metals. The method effe...
Additionally, this implies that the conversion of amides to other functional groups typically necessitates demanding experimental conditions and extended reaction durations. Specifically, the direct formation of esters from amides necessitates the application of highly acidic or alkaline conditions, which are...