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9a). This was also the case in anterior and posterior enterocytes, where the age-dependent shift along the PC1 axis was recovered under MetR condition (Supplementary Fig. 9b, d). However, the degree of the rescue of the age-related transcriptomic shifts varied greatly among clusters. It has...
et al. Neurogenesis-dependent remodeling of hippocampal circuits reduces PTSD-like behaviors in adult mice. Mol Psychiatry 29, 3316–3329 (2024). https://doi.org/10.1038/s41380-024-02585-7 Download citation Received06 November 2023 Revised18 April 2024 Accepted23 April 2024 Published08 May 2024 ...
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Importantly, newly generated neurons have particular physiological properties that make them more susceptible to behavioral-dependent synaptic plasticity [11]. Using retroviral labeling of newborn neurons with green fluorescence protein, Toni and colleagues have demonstrated that newborn neurons could form sy...
For this series of regressions, ability scores from one composite/domain were regressed on the year the assessment was completed using the subset data associated with that level of age; this process was completed for each of the composite and domain scores acting as the dependent variable. Doing...
where the superscript c refers to a conditional reduced-form demand relation. This relation allows for the possibility, for example, that the investment in E2 is dependent on E1. Life-Cycle Stage 3 (post-school years): The dynasty (primarily the youth/young adult, but with possible input fr...
utilisation during MetR (Figs.1j,3h). Considering that inhibitingSAM synthase(Sam-S) also results in a decrease inGnmtexpression46, there must be a system to downregulateGnmtmRNA upon detection of decreased SAM levels. The mechanism of this SAM-dependent regulation ofGnmtremains to be elucidated...
New neurons are continuously generated in the adult brain through a process called adult neurogenesis. This form of plasticity has been correlated with numerous behavioral and cognitive phenomena, but it remains unclear if and how adult-born neurons (abN