International Journal of Radiation BiologyDenisenko, M. F., Soldatenkov, V. A., Belovskaya, L. N. and Filippovich, I. V. (1989) Is the NAD-poly(ADP-ribose) polymerase system the trigger in radiation-induced death of mouse thymocytes? Int. J. Radiat. Biol. 56, 277-285....
- 《Bmc Evolutionary Biology》 被引量: 137发表: 2010年 Induction of poly(ADP-ribose) polymerase gene expression in lectin-stimulated human T lymphocytes is dependent on protein synthesis The poly(ADP-ribose) polymerase mRNA level in quiescent T lymphocytes was low, but was significantly higher ...
Using an assay to estimate the pADPRS level... BW Cherney,RJ Midura,AI Caplan - 《Developmental Biology》 被引量: 47发表: 1985年 ADP-ribosylation reactions : biology and medicine ADP-ribosylation reactions : biology and medicine edited by Osamu Hayaishi, Kunihiro Ueda (Molecular biology) ...
The recognition that DNA can be ADP ribosylated provides an unexpected regulatory level of how ADP-ribosylation contributes to genome stability, epigenetics and immunity. Yet, it remains unknown whether DNA ADP-ribosylation (DNA-ADPr) promotes genome sta
When infected with an ADP-deleted adenovirus, Jurkat cells survived and maintained viral DNA for greater than 1 month. These findings are consistent with the notion that the level of ADP expression determines whether lymphocytic cells proceed with a lytic or a persistent adenovirus infection. 展开 ...
PARP inhibitors (PARPi) are important tools for understanding the biology of ADPr signaling, and several PARPi are approved for use in cancer treatments. The review also covers our current knowledge on PARPi mode of action, with a particular focus on clarifying the enigmatic process known as ...
ADP ribosylation is the addition of one or more ADP-ribose moieties to a protein. From: Encyclopedia of Agriculture and Food Systems, 2014 About this pageSet alert Also in subject areas: Biochemistry, Genetics and Molecular Biology NeuroscienceDiscover other topics On this page Definition Chapters ...
Like the scientific history that every development of microscopy drastically advanced biology, the “lens” of phase separation would bridge spatiotemporal gaps of understanding between cell biology and molecular biology. We previously reported that apoptosis signal-regulating kinase 3 (ASK3; also known ...
Sulfur mustard (SM) is a chemical warfare agent leading to severe blistering of skin and mucosal surfaces, and as a long-term effect, to an increased risk for malignancies. At the molecular level, SM acts as a bifunctional alkylating agent, leading to DNA mono-adducts and di-adducts. This...
Bai, P. Biology of poly(ADP-Ribose) polymerases: The factotums of cell maintenance. Mol. Cell 58(6), 947–958 (2015). Article MathSciNet CAS PubMed Google Scholar Szanto, M. et al. Poly(ADP-ribose) polymerase-2: Emerging transcriptional roles of a DNA repair protein. Cell. Mol. ...