Synaptically localized cell adhesion molecules (SAMs), are multifunctional molecules that coordinate different aspects of synaptic development and function through specialized signalling or protein–protein interaction motifs. Neurexin–neuroligin signalling has a role in the development of pre- and postsynaptic...
doi:10.1016/S1569-2558(08)60051-XJohn J. HemperlyELSEVIERAdvances in Molecular & Cell BiologyHemperly JJ. Signaling by cell adhesion molecules in the nervous system. Adv. Mol. Cell. Biol. 1999;28:303-320.
Signaling through cell adhesion molecules have long been of interest because of their importance in embryonic development, homeostasis, immune responses, wound healing , and malignant transformation. However, it is only recently realized that cell adhesion mole... (展开全部) 我来说两句 短评 ···...
Cell-cell adhesion and cell-matrix adhesion are important for normal breast stem or transit amplifying cells, cell localizations and for normal breast tissue architecture. Cell surface adhesion receptors are also involved in outside-in and inside-out signaling, that affects regulation of cell growth,...
Cell adhesion is the process by which cells form contacts with each other or with their substratum through specialized protein complexes. Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through foca...
Cell–cell adhesion is mediated by members of the cadherin-catenin system and among them, E-cadherin and β-catenin are important adhesion molecules for epithelial cell function and preservation of tissue integrity. According to previous work [39] related to cDNA expression, the analysis revealed ...
Accordingly, a drop of a cell-free biosurfactant solution of L. rhamnosus was dispensed on oil. On this occasion, if the surfactant is not present in the liquid, the drop stands stable, meaning, from the hydrophobic sites, the polar water molecules are repulsed. Contrastingly, if the ...
In the endothelium, the TNF-α signaling pathway, which is regulated by nuclear factor kappa B (NF-KB), governs the expression of adhesion molecules such as sICAM-1 [12]. Many studies have found that women with PCOS have significantly higher ICAM-1, MCP-1 and TNF-α than women without ...
aGenistein has been shown to exert inhibitory effects on targets that are involved in almost every step of the metastatic cascade, including FAK,integrins, TGF-β signaling molecules, and MMPs, which together are critical to the processes of cell adhesion and invasion. Early positive clinical ...
Davies G, Jiang G, Mason MD (2000) Cell - cell adhesion molecules and signaling intermediates and their role in the invasive potential of prostate cancer cells. J Urol 163: 985 - 992Davies G,Jiang WG,Mason MD.Cell-cell adhesion molecules and signaling intermediates and their role in the ...