1、细胞粘附分子CellAdhesionMoleculesCAM 1.定义 是介导细胞与细胞或细胞与细胞外基质间相互接触和结合的一类膜表面糖蛋白分子。 以受体与配体方式相互作用,通过增加细胞间粘附作用和或传递信号而促进细胞的功能。一、基本概念选择素家族 selectin整合素家族 integrin粘蛋白样家族Ig家族 IgSF钙粘蛋白家族 cadherin尚未归类的...
主要依靠细胞粘附分子CelladhesionmoleculesCAMS.ppt,主要依靠细胞粘附分子直接将个细胞连接在一起缝隙连接允许相邻细胞的胞质溶胶间的小分子和离子在连接子通道中运动紧密连接在微绒毛下阻止大分子的扩散并且阻止水溶性小分子和离子穿越细胞间的上皮层还可以通过阻止细胞膜
医学课件细胞粘附分子CellAdhesionMoleculesCAM 第9章细胞粘附分子CellAdhesionMolecules,CAM 一、基本概念 1.定义 是介导细胞与细胞或细胞与细胞外基质间相互接触和结合的一类膜表面糖蛋白分子。以受体与配体方式相互作用，通过增加细胞间粘附作用和或传递信号而促进细胞的功能。2.分类选择素家族selectin整合素家族integrin粘...
•Cell–CellAdhesion：主要依靠细胞粘附分子(CelladhesionmoleculesCAMS)直接将2个细胞连接在一起；•Cell-MatrixAdhesion:靠粘着受体(Adhesionreceptor)将细胞与胞外基质连接在一起；Majorfamiliesofcell-adhesionmolecules(CAMs)6.2Majoradhesiveinteractionsthatbindcellstoeachotherandtotheextracellularmatrix 缝隙连接 紧密...
细胞粘附cam分子adhesionmolecules 1CellAdhesionMolecules,CAM2定义定义是介导细胞与细胞或细胞与细胞外基是介导细胞与细胞或细胞与细胞外基质间相互接触和结合的一类质间相互接触和结合的一类膜表面糖蛋白分子膜表面糖蛋白分子。。以以受体与配体受体与配体方式相互作用,通过方式相互作用,通过增加细增加细胞间粘附作用胞间...
N-CAMS and transmembrane adhesion molecules help mediate binding of cells to the ECM and each other! Two main ways in which animal cells are bound together: ?Connective tissue ?Epithelial cells. Figure 19-1 Molecular Biology of the Cell (? Garland Science 2019) Four functional classes of cell...
•PathwayGuidancetoLeadCellsHome:•Chemotaxisvs.Chemo-avoidance:•Ligands/Receptors/SecondMessengers•N-CAMSandtransmembraneadhesionmoleculeshelpmediate bindingofcellstotheECMandeachother!Twomainwaysinwhichanimalcellsareboundtogether:•Connectivetissue•Epithelialcells.Figure19-1MolecularBiologyoftheCell(©...
The selectins and integrins can also act as heterophilic cell-cell adhesion molecules: the selectins bind to carbohydrate, while the cell-binding integrins bind to members of the immunoglobulin superfamily. The integrins and integral membrane proteoglycans that mediate nonjunctional adhesion to the ...
proposedin1972bySingerThisdrawingillustrateswhycell-adhesionmoleculesmustbelinkedtothecytoskeletoninordertomediaterobustcell-cellorcell-matrixadhesion.Phosphatidylcholine,representedschematically(A),informula(B),asaspace-fillingmodel(C),andasasymbol(D).Thesecellscontainabundantendoplasmicreticulum,wheresecretedproteins...
2.3 Cell adhesion molecules and cell junction 2.4 Extracellular matrix and cell wall Chapter 3 Cytoplasm,ribosomes and RNAs 3.1 Structure and functions of cytoplasm 3.2 Ribosome 3.3 Ribozyme 3.4 Non-coding RNA Chapter 4 Endomembrane system,protein sorting and vesicle transport 4.1 Overview of endomembra...