Adenoviral Vectors for Gene Therapy is designed to educate and update gene therapists in the basics, pre-clinical, and clinical applications related to the use of adenoviral vectors for human gene therapy. The editors have a rich history in the use of adenoviruses as gene therapy agents ...
Adenoviral Vectors for Gene Therapy, Second Editionprovides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, ma...
Bangma CH. Targeting of adenoviral vectors for gene therapy of prostate cancer. Prostate Cancer Prostatic Dis 2000; 3: 308-312.Bangma, C.H. (2000). Targeting of adenoviral vectors for gene therapy of prostate cancer. Prostate Cancer Prostatic Dis 3, 308-312....
Gene TherapyGene DeliveryAdenoviral VectorHuman Gene TherapyRecombinant Adenoviral VectorVectors based on human adenovirus serotypes 2 (Ad2) and 5 (Ad5) of species C possess a number of features that have favored their widespread employment for gene delivery both invitro and invivo. However, the ...
Because HAdV vector effectively transduces cells, it has been widely used as gene delivery vectors of transgenes in the research fields of gene therapy and basic science. Therefore, HAdV vector is a feasible vehicle to deliver noncoding ribonucleic acids (ncRNAs) in mammalian cells. Invitro and...
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In the first generation of adenoviral vectors for gene therapy, the E1 region was replaced by foreign genetic information, e.g., the therapeutic gene. The absence of E1 renders the recombinant virus replication defective. Because E1 has been reported to trigger the transcription of other Ad gene...
Targeting CD46 enhances anti-tumoral activity of adenovirus type 5 for bladder cancer Int. J. Mol. Sci., 19 (2018), p. 2694 Google Scholar 27 W.S.M. Wold, K. Toth Adenovirus vectors for gene therapy, vaccination and cancer gene therapy Curr. Gene Ther., 13 (2013), pp. 421-433 ...
RECOMBINANT ADENOVIRAL VECTORS FOR HUMAN TUMOUR G
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 2001; 7: 33–40. Article CAS PubMed Google Scholar Lowenstein PR, Castro MG . Progress and challenges in viral vector-mediated gene transfer to the brain. Curr Opin Mol Ther 2002; ...