Adenoviral Vectors for Gene Therapy is designed to educate and update gene therapists in the basics, pre-clinical, and clinical applications related to the use of adenoviral vectors for human gene therapy. The editors have a rich history in the use of adenoviruses as gene therapy agents ...
Adenoviral Vectors for Gene Therapy, Second Editionprovides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, ma...
However, the use of recombinant Ad2- and Ad5-based vectors for gene therapy also suffers from a number of disadvantages. These vectors possess the tropism of the parental viruses, which infect all cells that possess the appropriate surface receptors, precluding the targeting of specific cell types...
Preface - Adenoviral Vectors for Gene TherapyDavid T. CurielJoanne T. DouglasELSEVIERAdenoviral Vectors for Gene Therapy
High-Capacity "Gutless" Adenoviral Vectors-Chapter 15:Technical Aspects and Applications Adenoviral vectors are promising gene transfer vehicles for different gene therapy applications. High-capacity adenoviral (HC-Ad) vectors address some of t... G Schiedner,PR Clemens,C Volpers,... - 《Current ...
Adenoviral vectors for in vivo gene delivery to oligodendrocytes: transgene expression and cytopathic consequences Gene Therapy 1999 6: 1360–1367 Article CAS PubMed Google Scholar O’Leary MT, Charlton HM . A model for long-term transgene expression in spinal cord regeneration studies Gene Therapy...
114. Adenoviral Vectors for Gene Therapy with Improved Entry of Malignant Glioma114. Adenoviral Vectors for Gene Therapy with Improved Entry of Malignant GliomaAn adenovirus serotype 35 (Ad35) vector, which is composed of whole Ad35 belonging to subgroup B, has gained interest as a promising vehi...
Bangma CH. Targeting of adenoviral vectors for gene therapy of prostate cancer. Prostate Cancer Prostatic Dis 2000; 3: 308-312.Bangma, C.H. (2000). Targeting of adenoviral vectors for gene therapy of prostate cancer. Prostate Cancer Prostatic Dis 3, 308-312....
Gene Therapy/ Molecular Pathology protooncogene mutation; Mesothelin mediated targeting of adenoviral vectors for ovarian cancer gene therapy; Analysis of transcription factors in human ... 被引量: 0发表: 2004年 A phase I clinical trial of single-dose intrapleural IFN This phase 1 dose escalation ...
Skeletal muscle represents an attractive target tissue for adenoviral gene therapy to treat muscle disorders and as a production platform for systemic expression of therapeutic proteins. However, adenovirus serotype 5 vectors do not efficiently transduce adult muscle tissue. Here we evaluated whether capsid...