Delayed start analysis of ADAS-Cog14 scores in patients mild AD from the EXPEDITION, EXPEDITION2, and EXPEDITION-EXT studies of solanezumab.Hong LiuSeifertScott W. AndersenIlya LipkovichKaren C. HoldridgeEric Siemers
ADAS—Cog totalSCOrecould mildandmoderateAD a of78%-82%anda of70%· classify efficiently.withsensitivity specificity 73%.Conclusion:OurresultsindicatethattheChineseversion isusefulfor ofAD.Itisrecom- ofADAS-Cogstaging thattheChineseversionof be for AD mended introduced the on ADAS-Cog monitoringdrug...
此外,低 tau 蛋白负荷患者的疗效指标结果不一致:接受 lecanemab 治疗的患者 CDR-SB 相比基线确实改善了,但 ADAS-Cog14(认知)和 ADCS MCI-ADL(功能)两项指标 lecanemab 治疗患者相比基线却都恶化了。这种背道而驰的结果无疑会影响疗效结论的可靠性。
Negative correlation can be seen between ADAS-Cog and MMSE (ρ = − 0.67, p < 0.001). (Fig. 2). According to the Youden Index (Y = 76.00%) and the square of the distance (d2 = 4.16%), the ideal cut-off score should be at 44/45 between HC and MCI patients (Table 1). ...
the ADAS-Cog, the MMSE, and the CDR-SOB, correspond.Results: Results indicated multiple inflections in CDR-SOB and ADAS-Cog scores within a given MMSE score, suggesting that the CDR-SOB and ADAS-Cog are more precise in measuring the severity of cognitive dysfunction than the MMSE.Conclusions...
The aim of this analysis was to determine whether there were any geographic differences in rater administration and/or scoring error rates on the ADAS-Cog. We reviewed data from four multi-national AD clinical trials in order to determine whether there were any geographic differences in rater ...
Sensitivity of memory subtests and learning slopes from the ADAS-Cog to distinguish along the continuum of the NIA-AA Research Framework for Alzheimer鈥檚 DiseaseABSTRACTDustin B HammersRalitsa V KostadinovaRobert J SpencerJean N IkangaFrederick W Unverzagt...
For each item, participants were asked whether they had been instructed to administer or score the ADAS-Cog in different ways between various protocols in which they had participated. Results: Twenty-six raters completed the survey. Participants varied in experience from 1 - 12 years of ...