Studies with some tocainide analogues having a primary amino group and a secondary amide demonstrated that these functional groups are required to give labile HFB derivatives. On the contrary, stable derivatives of tocainide were formed with heptafluorobutyryl chloride and N-methyl-bis(heptafluorobu...
Acetal 缩醛 [化]乙缩醛, 乙缩醛二乙醇 acet yl- 乙酰 Acetylide 炔化物 acid 酸 Active hydrogen compounds 活泼氢化合物 Acyl azide 酰叠氮 Acyl chloride 酰氯 Acyl cyanide 酰腈 Acyl fluoride 酰氟 Acyl halide 酰卤 Acyl iodide 酰碘 Acyl peroxide 酰基过氧化物 Acyl rtomide 酰溴 Acyl tosylate 酰基对...
Answer: The carboxylic acid first reacts with oxalyl chloride to form HCl and an anhydride, which then decomposes by a cyclic mechanism in which the chlorine atom of the intermediate attacks the carbonyl carbon atom of the original carboxylic acid. A concerted process in the third step releases...
ChemInform Abstract: Chemiluminescence of Organic Peroxides: Intramolecular Electron‐Exchange Luminescence from a Secondary Perester The reaction of an aminocoumarin carboxylic acid chloride (Coumarin 343) with 1-phenethyl hydroperoxide results in light emission that is easily detected w... J. VAN GOMPEL...
Transformation with sub- strates that contain an alkyl chain that bears a functionalizable polar group, such as an amide (10g), a silyl ether (10h) or a cyano unit (10i) proved to be exceptionally efficient (498% yield) and highly enantioselective (91:9–97:3 er). Rearrangements ...
Enantiomerically pure chiral amines and related amide derivatives are privilege motifs in many pharmacologically active molecules. In comparison to the well-established hydroamination, the transition metal-catalysed asymmetric hydrofunctionalization of e
2-(Trimethylsilyl)benzofuran, available quantitatively from benzofuran itself, reacts rapidly with primary, secondary, and tertiary aliphatic carboxylic acid chlorides in the presence of titanium (IV) chloride at low temperature to affor... Melvyn,Gill - 《Tetrahedron》 被引量: 36发表: 1984年 De...
Pd2dba3 CuCl cat 3-component [imine acylchloride, vinylstannane phenylstannane benzylstannane thiophenylstannane] syn N-allylamide [imine vinylation] & N-v... BA Arndtsen 被引量: 0发表: 2005年 Synthesis of Conjugated Materials Based on Benzodithiophene - Benzothiadazole and Their Application ...
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain N-acyl-{4-[(4-aryl-phenyl)sulfonylmethyl]
In filamentous fungi there is a single PPTase which modifies enzymes involved in primary and secondary metabolism.135,136 These PPTases are similar in function to Sfp-PPTases and often Sfp-type PPTases are used when investigating the function of NR-PKS domains in vitro.39,67 Alternatively, ...