Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.Enrique Luis Michelotti
Amine 胺 -amine 胺 Amino acid 氨基酸 amino- 氨基的 -ane 烷 anhydride 酐 anilino- 苯胺基 aquo- 含水的 -ase 酶 -ate 含氧酸的盐、酯 -atriyne 三炔 Azine 嗪 azo- 偶氮 benzene 苯 Betaine 甜菜碱 bi- 在盐类前表示酸式盐 bis- 双 -borane 硼烷 bromo- 溴 butyl 丁基 . -caboxylic acid 羧...
The second mole of starting ylide necessary for a transylidation may be substituted by triethylamine if the amine is a stronger base than the ylide, as is usual in the case of stabilized phosphoranes.156,165 Under the influence of the added amine or the original ylide hydrogen chloride may ...
Reactions ofphenylglyoxalwith primary amines have allowed the synthesis of some monoimines <84JCR(S)144>. α-Ketodicarboxylic acid chloride imine chlorides, which readily undergocyclizationtoN-heterocycles, can be prepared by α-addition ofdicarboxylic acidchlorides toisocyanides(Equation (20)) <86LA13...
The robustness and synthetic utility of this catalytic system were further demonstrated by gram-scale synthesis and subsequent derivatization of the product (Fig.5a). A 5 mmol-scale hydroarylation was performed successfully and the product (3a) was readily converted into the tertiary amine (5a) ...
Primary Examiner: ROTMAN, ALAN L Attorney, Agent or Firm: POLSINELLI PC (HOUSTON, TX, US) Parent Case Data: CONTINUING DATA This application claims benefit of 60/116,675 filed Jan. 21, 1999. Claims: What is claimed is: 1. An acyl derivative of 4-demethylpenclomedine represented by the...
2.A method for preparing a compound of O-acyloxime of claim 1 comprising:1) reacting a compound 2 with hydroxyamine in the presence of base to form a compound 3; and2) reacting the compound 3 prepared in the step 1) with acylchloride to form a compound 1,wherein,said compound 2 has...
N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase. Biochem. J. 379, 99–106 (2004). 25. Petrosino, S. et al. Diacerein is a potent and selective inhibitor of...
Primary Examiner: Brown, Johnnie R. Attorney, Agent or Firm: Conroy Jr., Edward A. Claims: I claim: 1. A compound selected from the group consisting of those of the formula: ##STR7## wherein the configuration of the double bond is cis or trans; R' is a moiety selected from the ...
C) can help to avoid side-reactions from occurring between the organometallic reagent and the ketone product.253Initial reports focused on coupling simple primary alkyl, alkenyl and arylzinc halides with thioesters using Pd catalysts.308This methodology generally displays excellent functional group toleranc...