Here we report the reaction of several semicarbazides, thiosemicarbazides and related acyl substituted hydrazides with oxalyl chloride and malonyl chloride. These reactions occur with the formation of heterocyclic products which are...doi:10.1002/chin.198923343COOLEY, J. H....
Initially, an acetylation reaction between a secondary amine and acetyl chloride produces 1-acetyl-2-methyl-1H-benzimidazole (compound 1) [18]. It is followed by the Claisen-Schmidt reaction, whereby the condensation takes place at the –COCH3 group due to the electronegative nature of oxygen. ...
the resulting product is reacted with an alkanolamine or diol in an inert liquid medium while passing a stream of hydrogen chloride gas therethrough. The amine hydrochlorides produced in this manner may be converted to the corresponding isocyanates by reaction with phosgene or other carbonyl di...
The reaction, for example, between a primary amine and ethylene oxide, yields a material of the formula type HO.CH2.CH2.NHR. Such amines may be reacted with detergent-forming carboxy acids to give suitable amides. Briefly, then, in a practical way amides can be derived from detergent-...
The exact function of tandem ACP domains in NR-PKS may be beginning to emerge as the investigation of recently characterized NR-PKS indicates their role is to not only to aid in the overall efficiency of polyketide biosynthesis but also to orientate polyketide substrates to allow reaction with a...
Acyl Chloride |有机化学 |with Alcohol and phenol 522021-04 2 Acyl chloride | 有机化学|hydrolysis 452021-04 3 Acyl Chloride |有机化学 | Intro of reaction 302021-04 4 Acyl chloride |有机化学 |Making from COOH 442021-04 5 Nitrogen Compound | Amino acid & zwitterion 492021-04 6 Nitrogen Co...
Acid chlorides followed a different reaction pathway when treated with either (81)148 or (77)149 as the source of (79). Although an intermediate analogous to that proposed for esters may be involved, (5), the increased capacity of the halogen as a leaving group results in chloride eliminatio...
In particular, acyl compounds of the present invention can be produced by reacting 4-demethylpenclomedine with an acylating agent such as an acyl chloride or acyl anhydride. If desired, such reaction can be carried out in the presence of a base. ...
This invention relates to a process for producing substituted acylating agents by the reaction of an enophile with an ene by the thermal route wherein (a) the molar ratio of the enophile to the ene is
Compounds of formula I can be prepared under standard reaction conditions well known in the art. For example, a carboxylic acid of formula II can be converted to the acid chloride by treatment with thionyl or oxalyl chloride in a solvent such as CH2 Cl2, then reacted with an amine of form...