Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.Enrique Luis Michelotti
57,129 Allyl chloride also reacted with acetylene and CO in the presence of tetracarbonylnickel to produce 2-cis,5-hexadienoyl chloride (equation 240).129,130,134 However, this acyl chloride underwent further reaction with nickel carbonyl and acetylene to give (148) (Section 50.3.5). (239)...
amine components<1997T8307, 1998BMC1845, 1998T2619, 2001T6215>. α-Acyl-N-H-imines have been prepared in good yields (>60%) by the reaction of various benzaldehydes withN-(n-octyl)-2,2,2-trifluoroacetimidoyl chloride<1995JFC247>. The treatment of substituted thiazolidines with DBU ...
sodium hydroxide (1.92 g; 48 mm) and anhydrous ethanol (6 ml) are refluxed for 1½ hr. The reaction mixture is concentrated to dryness, and the residue is extracted twice with methylene chloride (2×60 ml). The extract is washed with water and the organic layer, after...
Ynamine 炔胺 -yne 炔 Zwitterions 两性离子 二、有机合成中常见术语 1,4-addition 1,4-加成 Absolute configuration绝对构型 Abstraction夺取[反应] Achiral非手性[的] Aci form酸式 Acid-base catalyxed reaction酸性溶剂 Acid-base catalyzed reaction酸碱催化反应 ...
This invention relates to a process for producing substituted acylating agents by the reaction of an enophile with an ene by the thermal route wherein (a) the molar ratio of the enophile to the ene is
with a teflon-lined screw cap, removed from the glove box and the reaction was stirred at rt (22~26 °C) for up to 48 h (the mixture was stirred at 750 rpm, ensuring that the base was uniformly suspended). After the reaction was complete, the reaction mixture was directly ...
Then 2-oxazolidone (0.5 mmol) The reaction in THF was added slowly in the presence of n–BuLi (0.55 mmol, 0.2 mL hexane) under nitrogen at − 78 °C. After being stirred at − 78 °C for 10 min, a solution of acid chloride (0.55 mmol) in THF was...
This invention relates to a composition comprising: a mixture of a brine and a liquid oil, and (A) an emulsifying amount of (i) at least one reaction product of a hydrocarbyl-substituted succinic acylating agent, and at least one of (a) ammonia, (b) an alcohol, (c) an amine, (d...
13.1g (0.10 mol) of DL-leucine was neutralized with 50 ml of 2N-NaOH solution and to the solution were simultaneously added dropwise 17.1g (0.10 mol) of 2-bromopropionylchloride and 50 ml of 2N-NaOH solution at room temperature over one hour while stirring and maintaining the reaction mixtu...