Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.Enrique Luis Michelotti
In conclusion, we have developed an enantioselective hydroarylation ofN-acyl enamines, which provides access to an array of enantioenriched benzylamines, a biologically active pharmacophore. This reaction is based on a reductive NiH catalysis strategy. A wide range of functional groups on both theN-...
Aminal 缩醛胺 Amine oxide 氧化胺 Amine 胺 -amine 胺 Amino acid 氨基酸 amino- 氨基的 -ane 烷 anhydride 酐 anilino- 苯胺基 aquo- 含水的 -ase 酶 -ate 含氧酸的盐、酯 -atriyne 三炔 Azine 嗪 azo- 偶氮 benzene 苯 Betaine 甜菜碱 bi- 在盐类前表示酸式盐 bis- 双 -borane 硼烷 bromo- 溴 ...
Acyl chloride | 有机化学|hydrolysis 45 2021-04 3 Acyl Chloride |有机化学 | Intro of reaction 30 2021-04 4 Acyl chloride |有机化学 |Making from COOH 44 2021-04 5 Nitrogen Compound | Amino acid & zwitterion 49 2021-04 6 Nitrogen Compound | Amino acid & zwitterion ...
differing in either ketoester or amine components<1997T8307, 1998BMC1845, 1998T2619, 2001T6215>. α-Acyl-N-H-imines have been prepared in good yields (>60%) by the reaction of various benzaldehydes withN-(n-octyl)-2,2,2-trifluoroacetimidoyl chloride<1995JFC247>. The treatment of subs...
Double Nucleophilic Addition of Ketene Silyl (THIO)Acetals and Trimethylsilyl Cyanide to N-Allylideneamine 1 Results We have already published a double nucleophilic addition reaction of α,β-unsaturated imines with several nucleophiles such as ketene silyl acet... Isao,Mizoia,Iwao,... - 《复旦学...
The second mole of starting ylide necessary for a transylidation may be substituted by triethylamine if the amine is a stronger base than the ylide, as is usual in the case of stabilized phosphoranes.156,165 Under the influence of the added amine or the original ylide hydrogen chloride may ...
This invention relates to a process for producing substituted acylating agents by the reaction of an enophile with an ene by the thermal route wherein (a) the molar ratio of the enophile to the ene is at least 3:1 and (b) the reaction pressure is raised to above 20 psig at least ...
22 From the above discussion, the formation of a hypothetic intermediate (10) from the N- acyllactam and amine was presumed to be the rate-determining step, although the structure was ambiguous. The continuous reaction mechanism through the intermediate is ex- pressed in Scheme 3 and eq 4 ...
This invention relates to a process for producing substituted acylating agents by the reaction of an enophile with an ene by the thermal route wherein (a) the molar ratio of the enophile to the ene is