primarily activated CD4 T lymphocytesTöpfer, ANiemöller, MAssenmacher, MGmbh, Miltenyi BiotecGladbach, Bergisch
Approaches that enhance radiation effect may lead to improved clinical outcome and decrease toxicity. Here we investigated whether activated CD4+ T cells (aCD4) can serve as an effective radiosensitizer. CD4+ T cells were activated with anti-CD3 and anti
Next, ASC isolated by adhesion in culture were submitted to various stimuli or co-culture with activated CD4 T cells. Changes in gene expression and secretion profiles were studied by Q-PCR and ELISA. Neutrophil migration was measured through Transwell and involvement of the candidate pathways was...
Using fetal thymic organ cultures (FTOCs), the present study investigated the impact of recirculating T cells on the two major cell populations in the thymus, namely the thymocytes and the TECs. Co-culturing with activated T cells, especially CD4+T cells, had a significant inhibitory effect on...
Because naïve T cells are unable to import cystine due to the absence of cystine transporters, it has been suggested that T cell activation is dependent on cysteine generated by antigen presenting cells. The aim of this study was to determine at which phases during T cell activation exogenous...
Activated CD4 专利名称：Activated CD4 ▲ above + ▼ T cell ligand for a receptor on the surface of (ACT-4-L)发明人：ゴッドフライ，ウェイン,アングルマン，エドガージョージ 申请号：JP1995521040 申请日：19950206 公开号：JP3703834B2 公开日：20051005 专利内容由知识产权出版社提供 摘要： ...
Early appearance of activated CD4+ T lymphocytes and class II antigen-expressing cells in joints of DBA/1 mice immunized with type II collagen. Lab Invest 1988; 58:53±60.Holmdahl R, Jonsson R, Larsson P, Klareskog L: Early ... R Holmdahl - 《Laboratory Investigation》 被引量: 213发表...
Resting and activated human CD4+ T cells express functional 5-HT3 receptor.Elena MagriniIldikò SzabòAndrea DoniJavier CibellaAntonella Viola
A significant correlation was found only for the degree of organ involvement and the increase in CD4+ T cells coexpressing HLA-DR, as well as the increase in CD57 expression on CD8+ T cells. In conclusion, both CD4+ and CD8+ T-cell subsets were activated in WG. Cytotoxic CD8+ CD57+...
T cell-mediated responses have been implicated in the development of fibrosis, impaired lymphangiogenesis, and lymphatic dysfunction in secondary lymphedema. Here we show that CD4+ T cells are necessary for lymphedema pathogenesis by utilizing adopt