AAV-CAG-Cre-GFP (AAV9),即AAV9 serotype adeno-associated virus (AAV) expressing Cre-GFP,是一种可表达Cre和GFP融合蛋白的腺相关病毒,常用于注射小鼠等动物后进行基因编辑。CAG启动子是一种由巨细胞病毒(CMV)增强子和鸡β-肌动蛋白启动子组合而成的可以用于大多数基因编辑的高效启动子,驱动基因在真核细胞内...
28,29 We tested a clinical-grade AAV9-GFP, a vector comparable with AVXS-101, but with a GFP transgene instead of SMN, at the same weight-based dose. We chose to do an open injection technique to avoid any technical variability from ultrasound-guided injections (which are performed ...
RaBGGTBAAV9自噬肌萎缩侧索硬化(Amyotrophic lateral sclerosis,ALS)是目前较罕见的一种神经退行性疾病,可选择性侵犯大脑皮质锥体细胞,锥体束,脑干运动核团及脊髓灰质前角神经元,造成运动神经元的损伤及变性.流行病学统计数据显示,ALS年发病率约为0.4-2.6/10万,以散发病例为主(s ALS),但仍有约5%-10%的患者为家族...
C3013-250μl AAV-mCherry-GFP-LC3B (AAV9, 10^13vp/ml) 250μl 6195.00元 AAV-mCherry-GFP-LC3B (AAV9),即AAV9 serotype adeno-associated virus (AAV) expressing mCherry-GFP-LC3B fusion protein,是一种可表达mCherry-GFP-LC3B融合蛋白的腺相关病毒,用于注射小鼠等动物后进行细胞自噬(autophagy)检测。
Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery Danielle Weber-Adrian, Rikke Hahn Kofoed, Joseph Silburt, Zeinab Noroozian, Kairavi Shah, Alison Burgess, Shawn...
支支🇨🇳:。支支🇨🇳入驻抖音,TA的抖音号是,已有200个粉丝,收获了10030个喜欢,欢迎观看支支🇨🇳在抖音发布的视频作品,来抖音,记录美好生活!
2013. Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver. PLoS ONE 8, e75894.Piras BA, O'Connor DM, French BA. Systemic delivery of shrna by aav9 provides highly efficient knockdown of ubiquitously expressed gfp...
Robust XII motoneuron GFP expression was observed in the caudal XII nucleus after either single or dual AAV9 injection; initial observations suggest no differences in XII motoneuron transduction between the two delivery methods. With both approaches, GFP expression was primarily restricted to XII moto...
Furthermore, the onset time and survival time of SOD1G93A mice injected with AAV9-RabGGTB-GFP+ were delayed compared with those of mice without overexpression. At the same time, we also observed a decrease in SOD1 misfolded and glial overactivation in the lumbar spinal cord of these SOD1G...
C3013-250μl AAV-mCherry-GFP-LC3B (AAV9, 10^13vp/ml) 250μl 6195.00元 AAV-mCherry-GFP-LC3B (AAV9),即AAV9 serotype adeno-associated virus (AAV) expressing mCherry-GFP-LC3B fusion protein,是一种可表达mCherry-GFP-LC3B融合蛋白的腺相关病毒,用于注射小鼠等动物后进行细胞自噬(autophagy)检测。