A specific cell surface antigen of Streptococcus gordonii is associated with bacterial hemagglutination and adhesion to α2–3-linked sialic acid-containing receptors Infect. Immun., 65 (1997), pp. 5042-5051 Google Scholar 13 P. Shivshankar, C. Sanchez, L.F. Rose, C.J. Orihuela The Streptoco...
It is difficult to regard HMOs as alternative receptors to block the entry of EV71 due to the differences in structure between HMOs and annexin A2. However, it has been demonstrated that sialic acid (2–3)-linked and (2–6)-linked galactose from breast milk could protect the intestinal cell...
Microglia maintain homeostasis in the central nervous system through phagocytic clearance of protein aggregates and cellular debris. This function deteriorates during ageing and neurodegenerative disease, concomitant with cognitive decline. We combined CRISPR–Cas...
Expression of MUC1, Thomsen-Friedenreich antigen, Tn, sialosyl-Tn, and α2,6-linked sialic acid in hepatocellular carcinomas and preneoplastic hepatocellul... The expression of epithelial mucins and Thomsen-Friedenreich-related antigens in preneoplastic and neoplastic hepatocellular lesions was systema...
First, unlike the archetype Slc37 family member Slc37a4, which functions as a Pi-linked G6P antiporter coupled to G6Pases-a/b, the exchange activity of Slc37a2 is insensitive to the G6Pases inhibitor chlorogenic acid, indicating that Slc37a2 is not a physiological G6P transporter44. ...
当细胞恶变时,糖链的数量和性质亦随之发生改变,并可反应在对凝集素结合的能力上.凝集素是一类无免疫原性,能识别糖链结构的蛋白质,其结合的专一性类似于抗原抗体反应.根据凝集素的糖结合特异性,凝集素可分为七类:(1)D—甘露糖或(D—葡萄糖)组;(2)N—乙酰葡萄糖胺组;(3)N—乙酰半乳糖胺组;(4)D—半乳糖...
The staining pattern of the antibody specific for polysialic acid (a linear homopolymer of α-2,8-linked sialic acid) increased in the CA1 and DG subfields of the Hp of the Aβ((25-35)) group compared to the control group. Our results suggest that injection of Aβ((25-35)) causes...
Inflammation-dependent changes in alpha2,3-, alpha2,6-, and alpha2,8-sialic acid glycotopes on serum glycoproteins in mice. Glycobiology 15, 827–837 (2005). 24. Amano, M. et al. Tumour suppressor p16INK4a - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-...
LudgerTag DMB Sialic Acid Release and Labelling Kit,DMB唾液酸释放和标记试 货号:LT-KDMB-A1 | 规格:22 samples | 价格:¥0.00 | 品牌:Ludger NGA2 glycan (A2, G0),NGA2多糖标准品(A2, G0) 货号:CN-NGA2-10U | 规格:10 mg | 价格:¥0.00 | 品牌:Ludger NGA3 Glycan (A3), 2-AA Labell...
Disease mutations in CMP-sialic acid transporter SLC35A1 result in abnormal 伪-dystroglycan O-mannosylation, independent from sialic acid Binding of cellular 伪-dystroglycan (伪-DG) to its extracellular matrix ligands is fully dependent on a unique O-mannose-linked glycan. Disrupted O-mannosylation...