Background: ST6 GalNAc alpha-2,6-sialyltransferaseV/ST6GALNAC5 Gangliosides are acidic glycosphingolipids that contain one or more sialic acid residues (1). They are abundant in the nervous system, where they play crucial modulatory roles in cellular recognition, interaction, adhesio...
NEW BETA-GALACTOSIDE-ALPHA2,6-SIALIC ACID TRANSFERASE AND ITS PRODUCTIONPURPOSE: To produce in large quantities at low cost a new β-galactoside-α2,6- sialic acid transferase derived from microorganisms.YAMAMOTO TAKESHI山本 岳NAKASHIZU MOTOKO...
This selectively altered cell migration was caused by the loss of alpha2,6-sialic acid structures on c-Met. Moreover, STAT3 was dephosphorylated at tyrosine 705 in ST6Gal-I-knockdown (ST6Gal-I-KD) HCT116 cells. c-Met is the substrate of ST6Gal-I. The hyposialylation of c-Met can ...
; Disodium (2R,4S,5R,6R)-5-acetamido-2-[({[(2S,3S,4R,5R)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-3,4-dihydroxytetrahydro-2-furanyl]methoxy}phosphinato)oxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrah ydro-2H-pyran-2-carboxylate; CMP-Sialic Acid, Disodium Salt; CMP-...
The activity of beta-galactoside alpha2,6-sialyltransferase (ST6Gal.1), the enzyme responsible for the addition of sialic acid in alpha2,6-linkage to N-acetyllactosaminic (Gal beta1,4GlcNAc) units of glycoconjugates, is increased in the ... F Dall'Olio,M Chiricolo,JT Lau - 《Internation...
N-iodosuccinimide (NIS) in the presence of an organic acid was found to be effective for the activation of fully acylated thioglycosides leading to 1,2-tra... GH Veeneman,SHV Leeuwen,JHV Boom - 《Tetrahedron Letters》 被引量: 309发表: 1990年 A chemically synthesized sialic acid-containing ...
ST3 beta -Gal alpha -2,3-Sialyltransferase 1 (ST3GAL1, also known as SIAT4 and SIAT4A) is a 45 kDa member of glycosyltransferase family 29 that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The full length ST3GAL1is a type II Golgi...
Interestingly, the mature form of UT-A3 glycan contains significant amounts of sialic acid. We explored the enzymes responsible for directing UT-A3 sialylation. Sialyltransferase ST6GalI, but not ST3GalIV, catabolizes UT-A3 锟斤拷2,6-sialylation. Activation of protein kinase C (PKC) by PDB ...
Identification and functional expression of a second human β-galactoside α2,6-sialyltransferase, ST6Gal II. BLAST analysis of the human and mouse genome sequence databases using the sequence of the human CMP-sialic acid:β-galactoside α-2,6-sialyltransferase cDN... Krzewinski-Recchi,Marie-Ange...
Enhanced expression of an alpha2,6-linked sialic acid on MDCK cells improves isolation of human influenza viruses and evaluation of their sensitivity to a ... The extensive use of neuraminidase (NA) inhibitors to treat influenza virus infections mandates close monitoring for resistant variants. Cultu...