These variants have 84 unique mutations in Spike glycoprotein. To analyse such mutations, multiple sequence alignment of 77681 SARS-CoV-2 genomes of 98 countries over the period from January 2020 to July 2021 is performed followed by phylogenetic analysis. Also, characteristics of new emerging ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective against inflammation to treat lethal COVID-19 are still urgently needed. Here, we constructed ...
The coronavirus SARS-CoV-2 emerging from Wuhan, China has developed into a global epidemic. Here, we combine both human mobility and non-pharmaceutical interventions (social-distancing and suspected-cases isolation) into SEIR transmission model to understand how coronavirus transmits in a global enviro...
The COMPILE program was designed to accelerate the evaluation of CCP and grappled with the challenges of pooling IPD from different populations, a variety of health care systems, and 3 different control treatments in the context of evolving treatment strategies and emerging variants of SARS-CoV-2....
To investigate COVID-19 surveillance among pregnant women, the California Genetic Disease Screening Program conducted a screening performance and seroprevalence evaluation of maternal SARS-CoV-2 antibodies detected in banked newborn dried blood spots (DBS). We obtained seropositive results for 2890 newbo...
Due to the appearance of emerging variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) all around the world and their spread, the number of COVID-19 cases is rapidly increasing, and because of this, coronavirus disease (COVID-19)-associated morbidity and mortality continue t...
This cohort study conducted using nationwide registers assesses the risks of myocarditis and pericarditis after SARS-CoV-2 messenger RNA vaccinations in a
Yong Zhang aYang Pan bXiang Zhao aWeifeng Shi c dZhixiao Chen aSheng Zhang aPeipei Liu aJinbo Xiao aWenjie Tan aDayan Wang aBiosafety and Health
SARS-CoV-2, Including Addressing the Impact of Emerging Variants, During the COVID 19 Public Health Emergency8provided examples of CMC strategies for expediting development of these products. The CMC strategies described in these guidances can be organized into the t...
Syndrome coronavirus-2 (SARS-CoV-2) has developed various strategies to evade the antiviral impact of type I IFN. Non-structural proteins and auxiliary proteins have been extensively researched on their role in immune escape. Nevertheless, the detailed m