Receptors for neuronal and nonneuronal 5-hydroxytryptamine (5-HT; serotonin) are distributed throughout the autonomic nervous system (ANS), in sympathetic and parasympathetic neurons, the enteric nervous system (ENS), sensory afferent and central neurons regulating the ANS, and autonomic neuroeffector ...
Serotonin [5-hydroxytryptamine (5-HT1)] is an important neurotransmitter in the CNS that exerts its neuronal activity via 5-HT receptors.The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the central nervous system, 5-HT1A receptors exist in the cerebral cortex, hippoca...
5-Hydroxytryptamine Receptor 3A (5-HT3A) belongs to the super-family of ligand-gated ion channels. Serotonin receptors, other than 5-HT3 subtype belong to the super-family of G-protein coupled receptors.nThe 5-HT3 receptor is formed by five subunits arranged around a pore forming unit. R...
Higashi H. 5-hydroxytryptamine receptors on visceral primary afferent neurons in the nodose ganglion of rabbit. Nature (Lond) 1977; 267 :448–450. [ PubMed ]Higashi, H., and S. Nishi (1982) 5-Hydroxytryptamine receptors of visceral primary afferent neurones on rabbit nodose ganglia. J. ...
Demonstration of 5-hydroxytryptamine receptors through inhibition by methergoline in cat pial arteries in vitro.1In an attempt to characterize further the nature of the 5-hydroxytryptamine (5-HT)-induced contraction of intracranial vessels, cat's middle cerebral artery was exposed to this amine and ...
(nicotinic or muscarinic) or substance P. 5-HTP-DP was also an equally potent displacer of3H-5-HT from its binding sites on enteric membranes. It is concluded that the sites responsible for specific binding of3H-5-HT are enteric M or neural 5-HT receptors. These receptors differ from ...
Serotonin (5-HT) receptors are part of the G protein-coupled and ligand-gated ion channel families. 5-HT exerts its diverse actions by binding to cell surface receptors which can be classified into seven distinct families (5-HT, to 5-HT gamma) according to their structural diversity and mod...
5-Hydroxytryptamine (5-HT) increases heart rate in the spinal-transected cat by acting on 5-HT1-like receptors, since this effect is not modified by ketanserin or MDL 72222 but is blocked by methysergide [Saxena et al., 1985]. These 5-HT1-like receptors in the cat heart have been ...
aIn vivo evaluation of 18F-MNI698: an 18F-labeled radiotracer for imaging of serotonin 4 receptors in brain 18F-MNI698的活体内评估: 一台18F被标记的放射性指示器为5-羟色胺想象4种感受器官在脑子 [translate] ashaving cream 剃须膏 [translate] aAssociation between variants of 5-hydroxytryptamine ...
few years ago a technique was arranged to test the sensitivity of the 5-HT venomotor receptors in man ( Sicuteri et al. 1964). This technique (venoconstriction test: VCT) is based upon the high responsiveness to 5-HT of the vein. The method is highly sensitive, being able to detect ...