serotonin receptorcalcium oscillationsanti‐idiotypic antibodygliaIntracellular calcium responses of cultured rat Schwann cells to 5-hydroxytryptamine (5-HT) were examined using the calcium indicator dye fluo-3. Consistent changes in [Ca2+]i were observed with bath application of 5-HT and the basis ...
The 5-HT2Areceptor selective antagonist (R)-[2,3-di(methoxy)phenyl]-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol (M100907) (500 µg/kg, i.p.) fully blocked the HTR at every dose of DOM (0.615–10 mg/kg, i.p.) in C57BL/6J mice. M100907 (50 µg/kg, i.p.) ...
In experiment II, the most effective dose of NMDA (12?nmol) or vehicle was preceded by microinjections of vehicle or the 5-HT2A receptor selective antagonist R-96544 at different concentrations (0.5, 5 and 10?nM) in the DRN. Both proaversive and antinociceptive effects elicited by intra-...
上海玉博生物科技有限公司 主要致力于“Anti-5-HTR2B(5-hydroxytryptamine(serotonin)receptor 2B) 5-羟色胺受体2B(5-HT/seroton yb-1892R”的生产销售。多年的“Anti-5-HTR2B(5-hydroxytryptamine(serotonin)receptor 2B) 5-羟色胺受体2B(5-HT/seroton yb-1892R”生产与
(2006). Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in Japanese depressed patients . Neuropsychopharmacology 31 , 825–83110.1038/sj.npp.1300919 [ Cross Ref ]...
Association between 5-hydroxytryptamine 2A receptor gene polymorphism and postoperative analgesic requirements after major abdominal surgery. Aoki J,Hayashida M,Tagami M,Nagashima M,Fukuda K,Nishizawa D,Ogai Y,Kasai S,Ikeda K,Iwahashi K. Neuroscience Letters . 2010...
Migraine5HT2Ameta-analysissusceptibilityEpidemiologic studies have investigated the association of polymorphisms in 5-hydroxytryptamine type 2A receptor (5HT2A) gene and migraine susceptibility, but the results of those studies are incon...doi:http://dx.doi.org/10.3109/00207454.2014.888425Jian-Ming Peng...
Accumulated studies suggest that HTR and locomotor hyperactivity induced by DOM are mainly caused by the activation of serotonin 5-hydroxytryptamine 2A receptor (5-HT2Areceptor). However, the mechanisms underlying the biphasic dose response of HTR and locomotor activity induced by DOM, particularly ...
Among the tested compounds, several were potent and efficacious 5-HT(2C) receptor agonists with selectivity over both 5-HT(2A) and 5-HT(2B) receptors in functional assays. The most promising compound is 37, with 120- and 14-fold selectivity over 5-HT(2A) and 5-HT(2B), respectively (...
HT1F receptor Agonist5-HT2A receptor Agonist5-HT2B receptor Agonist5-HT2C receptor Agonist5-HT3A Agonist5-HT3AB Agonist5-HT4 receptor Agonist5-HT5A receptor Agonist5-HT6 receptor Agonist5-HT7 receptor AgonistD1 receptor AgonistD5 receptor AgonistProton-coupled Amino acid Transporter 1 Inhibitor...