抗体名:5HT2A_HUMAN; 5-hydroxytryptamine receptor 2A; HTR2A; HTR2; 5-HT-2; 5-HT-2A; Serotonin receptor 2A;靶点:详见说明书 宿主:Rabbit适应物种:详见说明书 克隆性:详见说明书浓度:1mg/ml 应用范围:WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)...
5HT2A receptor protein contains a PDZ domain-binding motif which is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a ...
5-HT2A receptors: location and functional analysis in intestines of wild-type and 5-HT2A knockout mice. Am J Physiol 2002; 282: G877-93.Fiorica-Howells E, Hen R, Gingrich J, Li Z, Gershon MD. 5-HT2A receptors: Location and functional analysis in intestines of wild-type and 5-HT...
5-HT2A受体从HTR2A基因接收编码指令。该研究显示,早期生长反应基因EGR3产生的蛋白质也需要5-HT2A受体的表达。EGR3的功能是与DNA结合,打开和关闭其他基因。研究结果表明,睡眠剥夺引起的刺激会触发EGR3与5-HT2A受体基因结合,并启动其mRNA指令的产生,...
5-羟色胺2A (5-HT2A)受体广泛分布于大脑,在感知、认知和精神疾病中发挥着关键作用。它也是药物产生迷幻效果的原因,如裸盖菇素(致幻蘑菇)和LSD。 精神分裂症是一种以知觉和认知障碍为特征的精神疾病。5-HT2A受体功能异常与包括精神分裂症在内的精神疾病有关。用于治疗精神分裂症的主要抗精神病药物以5-HT2A受体...
产品介绍:5HT2A receptor is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5HT2A receptor belongs to the G-protein coupled receptor 1 family and mediates its action by association with...
In this study, we demonstrate that either the rat or human 5-HT2Areceptors, when stably expressed and activated by agonists10,11,12,13in HEK293 cells, caused increased adhesion of these cells to a variety of natural substrates. Conversely, 5-HT2A-dependent increase in adhesion was consistently...
5~HT2A receptors antagonists enhanced the therapeutic effects of antidepressants such as selective serotonin reuptake inhibitors ( SSRIs) for treatment~resistant depression and reduced adverse reactions such as sexual dysfunction and sleep disorder. Several 5~HT2A receptor~targeted antidepressants were ...
Background:5HT2A receptor is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5HT2A receptor belongs to the G-protein coupled receptor 1 family and mediates its action by association wit...
4-Hydroxyamesergide was also a potent inhibitor of vascular 5-HT2 receptors after oral administration to rats. After oral administration, 4-hydroxyamesergide had a similar or slightly greater duration of activity than the parent molecule. 4-Hydroxyamesergide, again like amesergide, also blocked...