公开(公告)日: 1987-03-04 发明名称: 1 4-DIHYDROPYRIDINES 发明人: 申请人: 申请日期: 1987-01-29 申请公布日期: 1987-03-04 代理机构: 代理人: 地址: 摘要: 二、法律状态 暂无信息 三、权利要求 暂无信息 登录查看更多 打开APP,查看更多专利的权利要求、说明书更多...
同时,该中心手性能很好的转化为轴手性。该方法为具有广泛生物学活性的1,4-二氢吡啶的研究与制备奠定了良好的基础。 该研究以“Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4-Dihydropyridines by C(sp3)-...
1,4-Dihydropyridines: Effects of Chirality and Conformation on Their Activity About 10 years ago, minor changes in the structure of calcium antagonistic 1,4-dihydropyridines (Fig. 1, item 1) were found to lead to derivatives with diametrically opposed pharmacological effects (Fig. 1). The ...
1,4-DIHYDROPYRIDINES1,4-DIHYDROPYRIDINES 申请(专利)号: GB19870002016 申请日: 1987-01-29 专利号: GB2185982B 公开公告日: 1990-05-16 主分类号: A61K31/455 分类号: A61K31/455; A61K31/4427; A61P7/02; A61P9/08; A61P9/10; A61P9/12; C07D211/78; C07D211/90; C07D401/06; C07...
汉斯酯1,4-二氢吡啶(HEH)在Pd/C催化下可以将取代的芳香叠氮化合物还原为相应的取代苯胺,反应具有很好的选择性。 2)1,4-Dihydropyridine1,4-二氢吡啶 1.One-Pot Synthesis of 4-Aryl-1,4-dihydropyridines in Water;水溶液中4-芳基-1,4-二氢吡啶衍生物的一步合成法 2.The Influence of Aqueous Phase ...
该研究以“Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4-Dihydropyridines by C(sp3)-H Bromination”为题发表于Angewandte Chemie International Edition期刊上,同时相应成果也申请专利。该研究得到中国科学院青年创新促进会、中国科学院西部之光人才A类、以及四川省科技厅中央引导地方项目(2021...
该研究以“Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4-Dihydropyridines by C(sp3)-H Bromination”为题发表于Angewandte Chemie International Edition期刊上,同时相应成果也申请专利。该研究得到中国科学院青年创新促进会、中国科学院西部之光人才A类、以及四川省科技厅中央引导地方项目(2021...
Chiral PhosphoricAcidCatalyzed Enantioselective Desymmetrization of 1,4-Dihydropyridines by C(sp3)–H Bromination Min Han,Shi-qi Zhang,Xin Cui,Qi-wei Wang,Prof. Guang-xun Li,Prof. Zhuo Tang 文章的第一作者是成都生物研究所与成都有机化学研究所联合培养博士研究生生韩敏 ...
1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE 发明人: GOLDMANN, SIEGFRIED, DR.;STOLTEFUSS, JURGEN, DIPL.-ING.;FRANCKOWIAK, GERHARD, DR.;GROSS, RAINER, DR.;SCHRAMM, MATTHIAS, DR.;THOMAS, GUNTER, DR. BAYER ITALIA S.P.A. 申请人: 申请日期: 1986-06-09...
3-Formyl-1,4-dihydropyridines, process for their preparation and their pharmaceutical useThe present invention relates to 3-formyl-1,4-dihydropyridines of the general formula I in which R<1> represents phenyl which is optionally ... STOLTEFUSS JUERGEN DIPL.-ING.,FRANCKOWIAK GERHARD DR.,BOESHAGE...