weight lossManaging side effects (general information)For healthcare professionals Applies to zonisamide: oral capsule, oral suspension. General adverse events The most common adverse reactions to this drug are somnolence, dizziness, and anorexia.[Ref] ...
Patients should contact their clinician immediately if they develop symptoms of metabolic acidosis such as fast breathing (hyperventilation), fatigue, loss of appetite, irregular heart beat, palpitations, or unconsciousness. Potential for drowsiness, especially at higher dosages. Importance of advising pati...
Pharmacokinetics, clinical efficacy and the adverse effects of zonisamide are discussed in the article. The discussion is based on data from published preclinical studies, clinical trials, observational studies, systematic reviews and approved summary of product characteristics. Expert opinion. Zonisamide is...
The objective of this study was to evaluate the efficacy, tolerability, and retention rates for zonisamide (ZNS) in older adult patients with focal-onset epilepsy.Chart reviews of patients aged 60years and older with focal-onset epilepsy treated with ZNS in two tertiary epilepsy centers were ...
The empirical formula is C 8H 8N 2O 3S with a molecular weight of 212.23. Zonisamide USP is a white powder, pKa = 10.2, and is moderately soluble in water (0.80 mg/mL) and 0.1 N HCl (0.50 mg/mL). The chemical structure is: Zonisamide is supplied for oral administration as ...