Human colon cancerEpithelioid organizationEpithelioid disorganization is a hallmark of gastrointestinal cancers and is believed to be associated with malignant phenotypes such as invasiveness and the potentiality for metastasis. Although tight junctions (TJs) are known to be crucial for the maintenance of ...
Positive IHC detected in mouse kidney tissue, mouse colon tissueNote: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 Positive IF/ICC detected in MCF-7 cells Freshly prepared samples are recommended. 推荐稀释比 Ap...
Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 82870-1-RR (ZO-1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82870-1-PBS in a ...
Methods The clinical data and colonic biopsies of UC in Shengjing Hospital of China Medical University from January 2014 to October 2017 were collected as the experimental group, and 80 cases were treated by pathology, and 20 cases of normal distal colon after resection were confirmed as the ...
Except for normal control group, those groups were given colon perfusion of acetic acid to induce PI-IBS model. After modeling, they were given relevant medicine intragastrically once a day for consecutive 5 days. The expression of ZO-1 and Occludin [by IOD] and their distribution were ...
( 30mg /kg) inthebackofthenecktoinduceCRC ; theNCgroupreceivedanequalvolumeofnormalsaline.Allratsweresacrificedattheendofthe39thweek.ThecolontissueandtheCRCtissuewerecollectedfromtheratsintheNCgroupandtheothergroups , re-spectively , tomeasuretheexpressionofzo-1andoccludinbyimmunohistochemistryandthe...
These findings strongly indicate that MGAT5/GnT-V expression is significantly greater in CRC tissues than in normal colon tissues. Fig. 1 Upregulation of MGAT5 is correlated with a poor prognosis and EMT in CRC patients. A Dot plots were generated to illustrate the expression profile of the ...
感染后肠易激综合征 回盲部 结肠 IL-17 occludin ZO-1 动态改变 post-infectious irritable bowel syndrome ileocecus colon IL-17 occludin ZO-1 dynamic changes DOI: CNKI:SUN:ZSYK.0.2018-03-004 年份: 2018 收藏 引用 批量引用 ...
Immunoblot analysis demonstrated that cingulin and ZO-1 are immunologically unrelated and that, in the colon, cingulin is a single polypeptide with a molecular mass of 140 kDa. Immunofluorescent localization of cingulin and ZO-1 in confluent monolayers of MDCK cells showed identical staining patterns...
Claudin-1 regulates cellu⁃ lar transformation and metastatic behavior in colon cancer[J]. J Clin Invest, 2005, 115(7): 1765-1776. 4 Arabzadeh A, Troy TC, Turksen K. Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis[J...