The unique Zn domain, adjacent to the active site of CT, makes for a unique target for the development of novel antibiotics capable of highly specific binding and presumably marginal toxicity.doi:10.1096/fasebj.23.1_supplement.503.2Glen Meades...
coli. Fep1 WT and cysteine mutants, either as the full-length protein or as the DNA-binding domain (amino acid residues 1–208) with a Flag tag at the N-terminus were cloned between NcoI and SalI in pET28a (Novagen) and expressed in E. coli BL21(DE3). Cells were induced with ...
Becker KG, Lee IJ, Nagle JW, Canning RD, Gado AM, Torres R, Polymeropoulos MH, Massa PT, Biddison WE, Drew PD: C2H2-171: a novel human cDNA representing a developmentally regulated poz domain/zinc finger protein prefentially expressed in brain Int J Dev Neurosci 15:891–899 (1997). ...
英文名字 ZNF96 (Zinc Finger Protein 96, KIAA0426, Zinc Finger and SCAN Domain Containing Protein 12, ZSCAN12, Zinc Finger Protein 305, ZNF305)供应商 MyBioSource产品货号 MBS606645产品报价 ￥询价/0.1mg ￥询价/5x0.1mg ￥询价/其它规格产品说明书 点击查看...
This domain contains 4 Zn fingers of the 2Cys + 2His type that are homologous to Zn fingers found in the C. elegans Pag-3 protein (87% identity; Jia et al. 1997) and the vertebrate Gfi-1 protein (87% identity; Gilks et al. 1993). The Pag-3 protein has been shown to contain ...
C-terminal retroviral-type zinc finger domain from the HIV-1 nucleocapsid protein is structurally similar to the N-terminal zinc finger domain Biochemistry, 30 (1991), pp. 6342-6349 CrossrefView in ScopusGoogle Scholar 33 M.D. Delahunty, T.L. South, M.F. Summers, R.L. Karpel Nucleic ac...
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targeting the DDK to dif f erent groups of origins and substrates. Here we report a genome-wide analysis of origin fi ring in a budding yeast mutant, dbf4-zn, lacking the Zn 2+ fi nger domain within the C-terminus of Dbf4. At one group of origins, which we call dromedaries, we ...
Conversion of Antennapedia Homeodomain to Zinc Finger-like Domain: Zn(II)-Induced Change in Protein Conformation and DNA Binding 来自 ACS 喜欢 0 阅读量: 22 作者:Yuichiro,Hori,Yukio,Sugiura 摘要: From the standpoint of protein dynamics and metalloprotein design, it is interesting to create an...
The goal of this study was to dissect the regulatory role of the multidomain Rad18 in DNA damage bypass using a structure-function based approach. Investigating deletion and point mutant RAD18 variants in yeast genetic and yeast two-hybrid assays we show that the Zn-finger of Rad18 mediates ...