zinc finger motif (锌指结构模序) 相关知识点: 试题来源: 解析 这类蛋白因子往往含有几个相同的指结构,每一个指结构具有以下的保守序列:Cys-X2-4-Cys-Phe-X5-Leu-X2-His-X3-His。这段保守序列中的两个半胱氨酸残基和两个组氨酸残基与锌离子形成配位键,形成环,因此称为锌指,上述具有Cys和His的指结构称...
【答案】：锌指基序模体(zinc finger motif)：是真核细胞中，一种序列特异性DNA结合蛋白的结构模体。这种蛋白质含有数个有规律的锌指重复单位，Cys2/His2锌指单位有30个氨基酸残基组成，其中一对半胱氨酸和一对组氨酸与Zn2+形成配位键，每个锌指的C端形成α螺旋负责与DNA结合，蛋白质通过上述锌指单位与...
By analogy, involvement in nucleic acid recognition has been implied for proteins that contain two cysteines and two histidines, spaced in accordance with the zinc finger motif. In this study we identify sequence dependent characteristics that are conserved in the DNA-binding zinc fingers and are ...
zinc finger motif (锌指结构模序) 正确答案 这类蛋白因子往往含有几个相同的指结构,每一个指结构具有以下的保守序列:Cys-X2-4-Cys-Phe-X5-Leu-X2-His-X3-His。这段保守序列中的两个半胱氨酸残基和两个组氨酸残基与锌离子形成配位键,形成环,因此称为锌指,上述具有Cys和His的指结构称为Cys2/His2指。
The zinc finger DNA-binding motif is common to many transcription factors in thehuman genome. The first zinc finger domains were identified in the structure ofXenopustranscription factor IIIAin 1985. This motif consists of a relatively shortα-helix and a two-stranded antiparallelβ-sheet (Figure ...
百度试题 题目锌指模型(zinc finger motif) 相关知识点: 试题来源: 解析 Caspase蛋白酶 反馈 收藏
近观两个金属离子结合位点:一者结合位是为典型的锌指结构(Zinc-finger motif),由四个半胱氨酸(Cysteine)分别为Cys104、Cy… etds.lib.ncku.edu.tw|基于 1 个网页 3. 锌指模式 三、染色质蛋白 ②锌指模式(Zinc-finger motif) ? 如转录因子Ⅲ(TFⅢA)。 ? 这类蛋白在与DNA结合的结构域 由多个有规 … ...
Beyond zinc fingers: steroid hormone receptors have a novel structural motif for DNA recognition The highly conserved DNA-binding domain of the steroid hormone receptors contains two 'zinc finger'-like sequence motifs. The three-dimensional structure i... JWR Schwabe,D Rhodes - 《Trends in Biochemi...
Zinc Finger Zinc fingers are encoded by approximately 3% of the human proteome and are the most common DNA-binding motif in eukaryotes. Transcription factors often use zinc fingers to mediate protein–DNA interactions. The most common zinc finger motif consists of a two-stranded anti-parallel β-...
锌指结构基元(zinc finger motif) 只看楼主 收藏 回复鳞之趾 四年级 7 这类蛋白因子往往含有几个相同的指结构, 每一个指结构具有以下的保守序列: Cys-X2-4-Cys-Phe-X5-Leu-X2-His-X3-His。这段保守序列中的两个半胱氨酸残基和两个组氨酸残基与锌离子形成配位键, 形成环, 因此称为锌指, 上述具有...