Molecular Characterization of a Novel Fibronectin-binding Protein of Streptococcus pyogenesStrains Isolated from Toxic Shock-like Syndrome Patients Group A has surface-located fibronectin (Fn)-binding proteins known to be a major virulence factor, which adheres to and invades host cells. We present a...
Like YTHDF1, the Pho92 YTH domain bound to m6A RNA without obvious sequence preference (Table 1). However, Tyr397 of YTHDF1 corresponded to Ser163 in Pho92 (Figs. 1A, 3D, and 6A); thus Pho92 would potentially recognize the nucleotide at −1 position with a pocket different from ...