N6-Methyladenosine (m6A) is the most abundant internal modification in RNA and is specifically recognized by YT521-B homology (YTH) domain-containing proteins. Recently we reported that YTHDC1 prefers guanosine and disfavors adenosine at the position preceding the m6A nucleotide in RNA and ...
One part of this work shows that the YTH (YT521-B Homology) domain previously identified by comparing protein sequences with rat YT521-B is a novel RNA binding domain. This novel RNA binding domain is found in 174 proteins expressed in eukaryotes and is characterized by 14 invariant residues...
Genome-Wide Identification and Expression Analysis of Members in the YT521-B Homology Domain-Containing RNA Binding Protein Family in Ginkgo bilobaGENETIC regulationRNA modification & restrictionRNA-binding proteinsABSCISIC acidGENE expressionN6-methyladenosine (m6A) is a widespread post-transcriptional ...